Epstein-Barr virus (EBV) infection is more likely to be associated with all the following malignancies EXCEPT

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Question 1 of 5

Epstein-Barr virus (EBV) infection is more likely to be associated with all the following malignancies EXCEPT

Correct Answer: B

Rationale: The correct answer is B) nasopharyngeal T-cell lymphoma. Epstein-Barr virus (EBV) infection is known to be associated with several malignancies, including Burkitt lymphoma, carcinoma, and Hodgkin lymphoma. However, nasopharyngeal T-cell lymphoma is not typically associated with EBV infection. In the context of pediatric nursing, understanding the relationship between viral infections like EBV and malignancies is crucial for providing comprehensive care to pediatric patients. This knowledge can help nurses anticipate potential complications, monitor for signs and symptoms of malignancies, and collaborate with the healthcare team to ensure timely diagnosis and treatment. By knowing which malignancies are more likely to be associated with EBV, nurses can play a key role in promoting early intervention and improved outcomes for pediatric patients at risk.

Question 2 of 5

A 6-year-old child complains of bilateral thigh pain, motor weakness, and some sensory deficits of both lower limbs; he has a history of bladder dysfunction over the past 2 weeks; MRI of the spinal cord shows a mass arising from the filum terminale and conus medullaris causing some pressure effect. A CNS tumor is suspected. Which of the following tumor is MOST likely arising in such site?

Correct Answer: C

Rationale: In this scenario, the correct answer is C) myxopapillary ependymoma. Myxopapillary ependymomas are typically slow-growing tumors that arise in the filum terminale and conus medullaris region of the spinal cord, which explains the symptoms of bilateral thigh pain, motor weakness, sensory deficits in the lower limbs, and bladder dysfunction in the 6-year-old child. These tumors are commonly associated with this specific location in the spinal cord. Regarding the incorrect options: A) Medulloblastoma is a malignant brain tumor that arises in the cerebellum, not in the spinal cord as seen in this case. B) Anaplastic astrocytoma is a type of brain tumor that arises from astrocytes in the brain, not in the spinal cord. D) Choroid plexus carcinoma is a rare and aggressive brain tumor that arises in the choroid plexus of the brain, not in the spinal cord. Educational context: Understanding the specific locations where different CNS tumors arise is crucial in pediatric nursing practice to accurately assess and manage symptoms in pediatric patients. This knowledge helps in differentiating between various tumor types based on clinical presentations and imaging findings, leading to timely diagnosis and appropriate treatment interventions.

Question 3 of 5

Childhood primary brain stem tumors are a heterogeneous group of tumors; the outcome usually depends on the tumor location. Which tumor, depending on the site of tumor, carries the worst prognosis?

Correct Answer: D

Rationale: In pediatric nursing, understanding childhood primary brain stem tumors is crucial for providing effective care. The correct answer is D) diffuse intrinsic. Diffuse intrinsic pontine glioma (DIPG), a type of diffuse intrinsic tumor, carries the worst prognosis due to its location in the brain stem, specifically the pons. This location makes surgical removal nearly impossible, leading to poor outcomes. Option A) focal dorsally exophytic tumors may have a better prognosis as they are more accessible for surgical intervention compared to diffuse intrinsic tumors. Option B) cervicomedullary diffuse intrinsic tumors, although diffuse intrinsic, are not as common as pontine gliomas and may have slightly different prognostic outcomes, making them a less definitive answer. Option C) none of the above is incorrect as there is a tumor type, diffuse intrinsic, known for its poor prognosis based on location. Educationally, this question highlights the importance of understanding the impact of tumor location on prognosis in pediatric brain tumors. It emphasizes the need for nurses to be knowledgeable about different tumor types and their implications for patient outcomes to provide holistic care to pediatric oncology patients.

Question 4 of 5

Renal cell carcinoma (RCC) is rare in children, accounting for <5% of all renal tumors. All the following are true regarding RCC in children EXCEPT

Correct Answer: E

Rationale: In this question, the correct answer is E, which is not listed as an option. Renal cell carcinoma (RCC) in children is indeed a rare condition, accounting for less than 5% of all renal tumors. The other options listed in the question are all true statements regarding RCC in children. Option A is correct because patients with RCC may present with symptoms such as frank hematuria, flank pain, and/or a palpable mass. Option B is also correct as RCC can be asymptomatic and may be incidentally detected. Option C is true as RCC in children has the potential to metastasize to various organs including the lungs, bone, liver, and brain. Option D is also accurate as RCC can be associated with von Hippel-Lindau disease, a genetic disorder that predisposes individuals to various tumors, including RCC. Educationally, understanding the presentation, diagnosis, and associations of RCC in children is crucial for healthcare providers working in pediatric oncology or nephrology. Recognizing the signs and symptoms, risk factors, and potential metastatic sites can aid in early detection, appropriate management, and improved outcomes for pediatric patients with RCC.

Question 5 of 5

Of the following, the WORST prognostic factor in pediatric osteosarcoma is

Correct Answer: B

Rationale: In pediatric osteosarcoma, the worst prognostic factor is a poor histologic response to treatment (Option B). This is because the histologic response to initial chemotherapy is a strong predictor of long-term outcomes. A poor response indicates that the tumor is resistant to treatment, leading to a higher risk of recurrence and poorer survival rates. Option A, primary pelvic bone tumor, is not the worst prognostic factor as the location of the tumor alone does not determine the response to treatment or the overall prognosis. Option C, bony metastases at diagnosis, is a negative prognostic factor but not as significant as the histologic response to treatment. Option D, lung metastases at diagnosis, is a serious factor but can still be managed with aggressive treatment protocols. In an educational context, understanding prognostic factors in pediatric oncology is crucial for nurses caring for children with cancer. Recognizing the impact of histologic response on outcomes helps nurses anticipate the course of treatment, support families through difficult decisions, and provide holistic care to pediatric oncology patients. By grasping the significance of prognostic factors, nurses can contribute to better outcomes and improved quality of life for their patients.

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