Effect of diabetes on foetus includes all except:

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: A

Rationale: Acromegaly is the condition characterized by the enlargement of the bones of the hands, feet, and face due to the overproduction of growth hormone in adults. This excess growth hormone typically comes from a benign tumor in the pituitary gland, leading to the gradual enlargement of these body parts. Cushing syndrome, on the other hand, is caused by prolonged exposure to high levels of cortisol and is not directly related to bone enlargement. Gigantism is the condition of excessive growth in height due to overproduction of growth hormone occurring in children before the closure of growth plates. Myxedema is a term used to describe severe hypothyroidism and is not directly associated with bone enlargement.

Correct Answer: B

Rationale: Myxoedema coma is a severe form of hypothyroidism that can lead to the slowing down of various body functions, including reduced heart rate (bradycardia). As the condition progresses and the body's metabolism becomes more depressed, one of the compensatory mechanisms is an increase in heart rate (tachycardia) to try to maintain adequate tissue perfusion. Therefore, tachycardia is a characteristic feature of myxoedema coma, rather than hypertension or euthermia which are not typically associated with this condition. Hypoventilation is also a common feature of myxoedema coma due to the decreased metabolic rate and respiratory drive.

Correct Answer: C

Rationale: Autonomic neuropathy in diabetes can manifest with various symptoms, such as retrograde ejaculation (A), gustatory sweating (B), and hypoglycemic unresponsiveness (D). Mononeuritis multiplex (C) is not typically associated with autonomic neuropathy in diabetes. Mononeuritis multiplex is a condition characterized by damage to at least two separate nerve areas resulting in weakness, pain, and sensory loss. Autonomic neuropathy in diabetes tends to affect the autonomic nerves that control involuntary bodily functions, leading to symptoms such as gastrointestinal issues, cardiovascular abnormalities, and sexual dysfunction, but mononeuritis multiplex is not a common feature of this condition.

Correct Answer: A

Rationale: Myxoedema is a term used to describe severe hypothyroidism. The characteristic features of myxoedema include sinus bradycardia (choice B), solid oedema (choice C), and madarosis (choice D), which refers to loss of eyebrows and eyelashes. However, a butterfly rash is not a typical feature of myxoedema. A butterfly rash is commonly associated with conditions like systemic lupus erythematosus rather than myxoedema.