ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
Edward jennar vaccinated against smallpox using...?
Correct Answer: D
Rationale: Edward Jenner used cowpox virus to vaccinate against smallpox, leveraging cross-immunity between the related viruses.
Question 2 of 5
Somatic hypermutation in the Immunoglobulin (Ig) variable region occurs...?
Correct Answer: C
Rationale: Somatic hypermutation occurs in B cells during their mitosis and differentiation in the bone marrow or lymphoid tissues, enhancing antibody affinity.
Question 3 of 5
Defects in Macrophage to kill bacteria that synthesis Catalase; this called?
Correct Answer: A
Rationale: Chronic granulomatous disease results from defective NADPH oxidase, impairing macrophages' ability to kill catalase-producing bacteria.
Question 4 of 5
Matching: Complement deficiency - Recurrent neisserial infection
Correct Answer: A
Rationale: Deficiencies in C5, C6, C7, C8, or C9 impair the membrane attack complex, leading to recurrent Neisseria infections (e.g., meningococcus). Properdin stabilizes the alternative pathway but is less directly linked to neisserial susceptibility compared to terminal complement deficiencies.
Question 5 of 5
Matching: Immunodeficiency - High frequency of autoimmune disorders
Correct Answer: C
Rationale: CVID is associated with a high frequency of autoimmune disorders due to immune dysregulation.