ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Each polypeptide chain (heavy and light) on immunoglobulin has a variable (V) and constant (C) region. Immunoglobulin chains are encoded by that is/are rearranged during development to assemble a functional gene encoding either a heavy or a light chain.
Correct Answer: C
Rationale: Immunoglobulin genes in B cells are encoded by sets of V, D, and J gene segments that rearrange during development.
Question 2 of 5
Which of the following TCR genetic chains contain D-segments, similar to immunoglobulin heavy chains?
Correct Answer: C
Rationale: Beta (β) and delta (δ) chains contain D-segments, similar to immunoglobulin heavy chains.
Question 3 of 5
A TCR complex is comprised of the TCR, CD3 molecules, and which of the following CD3 chains?
Correct Answer: D
Rationale: The TCR complex includes two zeta ζ) chains as part of the CD3 signaling complex.
Question 4 of 5
Class III MHC genes encode for which of the following?
Correct Answer: C
Rationale: Class III MHC genes encode complement components, not T cells or cytokines.
Question 5 of 5
Evidence is accumulating showing that polymorphism in the MHC may be advantageous. Homozygosity at HLA class I has been shown to be a(n) with respect to HIV/AIDS. Similarly, there is evidence that homozygosity at HLA class II the risk of hepatitis B virus infection persisting.
Correct Answer: D
Rationale: Homozygosity at HLA class I is a disadvantage for HIV/AIDS, and at class II increases hepatitis B persistence.