Each of the following statements about Neisseria meningitidis is correct, EXCEPT

Correct Answer: C

Rationale: The correct answer is C because there is no obligatory vaccine for Neisseria meningitidis in Bulgaria. The rationale for this is that while vaccines are available for meningococcal disease, they are not mandatory in Bulgaria. Therefore, this statement is incorrect. A: This statement is correct as Waterhouse-Friderichsen syndrome can occur during meningococcemia due to rapid progression of the infection leading to adrenal gland failure. B: This statement is incorrect as Neisseria meningitidis is most common in infants, children, and adolescents, with a second peak in young adults. D: This statement is correct as Neisseria meningitidis is transmitted through respiratory secretions, such as coughing or kissing, especially in close contacts like household members or roommates.

Correct Answer: B

Rationale: The correct answer is B because Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae are the most common causative agents of bacterial meningitis. Streptococcus pneumoniae is a leading cause in adults, Neisseria meningitidis is common in adolescents and young adults, and Haemophilus influenzae is more frequent in children. The other choices, Rubella virus (C) and Herpangina (D), are not bacterial agents known to cause meningitis.

Correct Answer: B

Rationale: The correct answer is B because there are two types of herpes simplex virus: HSV-1 and HSV-2. HSV-1 typically causes oral herpes, while HSV-2 usually causes genital herpes. Choice A is incorrect because there is more than one type. Choices C and D are also incorrect as there are only two types of herpes simplex virus known to infect humans.

Correct Answer: D

Rationale: The correct answer is D, Formation of CD4+ cells. In autoimmune reactions, CD4+ cells are actually involved in the immune response. Here's the rationale: 1. CD4+ cells are helper T cells that play a crucial role in activating other immune cells in autoimmune reactions. 2. Decreased functional activity of T-suppressors (Choice A) is typical in autoimmune reactions as it leads to unchecked immune responses. 3. Loss of tolerance for T-helpers and B-lymphocytes (Choice B) is common in autoimmune reactions, where the immune system mistakenly attacks self-cells. 4. Ag released by normally isolated tissues (Choice C) is a typical mechanism in autoimmune reactions where self-antigens trigger immune responses.

Correct Answer: A

Rationale: The correct answer is A: Staphylococcus saprophyticus. This bacterium is the second most common cause of cystitis in healthy sexually active women after E. coli. Staphylococcus saprophyticus is commonly found in the gastrointestinal and genital areas. It has a unique ability to adhere to uroepithelial cells, making it a common pathogen in urinary tract infections. Proteus mirabilis is more commonly associated with complicated UTIs, especially in catheterized patients. Pseudomonas aeruginosa is more commonly seen in hospitalized or immunocompromised patients. Klebsiella pneumoniae is typically associated with UTIs in elderly patients or those with structural abnormalities in the urinary tract.