During the regular sanitary epidemiological inspection of a pharmacy, the bacteriological analysis of air was performed. The air was found to have bacilli, yeast fungi, hemolytic streptococci, micrococci. Which of the detected microorganisms indicate the direct epidemic danger?

Correct Answer: A

Rationale: The correct answer is A: Haemolytic streptococci. Hemolytic streptococci are known to cause serious infections in humans, including strep throat and skin infections. These bacteria have the potential to spread rapidly and cause epidemics. Bacilli are a broad category of bacteria and not all are necessarily harmful. Micrococci are commonly found on human skin and are generally harmless. Yeast fungi are also commonly found in the environment and are not typically associated with causing epidemics. Therefore, the presence of hemolytic streptococci in the air of a pharmacy indicates a direct epidemic danger due to their pathogenic nature and potential to cause widespread infections.

Correct Answer: D

Rationale: The correct answer is D: mixed infection. In a mixed infection, multiple infectious agents establish themselves at the same site, leading to a complex and diverse infection. This type of infection can involve different types of pathogens such as bacteria, viruses, fungi, and parasites. It can be challenging to diagnose and treat due to the presence of multiple pathogens. A: Chronic infection refers to an infection that persists over a long period but is typically caused by a single pathogen. B: Necrotizing infection is characterized by rapid tissue destruction but does not necessarily involve multiple infectious agents. C: Fatal infection does not specify the presence of multiple infectious agents, it simply implies that the infection leads to death. In summary, the correct answer, mixed infection, is the only choice that specifically describes the scenario of multiple infectious agents establishing themselves at the same site.

Correct Answer: A

Rationale: The Burri-Gins staining technique is used to identify capsule formation in bacteria. Capsules are protective layers around bacteria that can be visualized using this staining method. Capsules are important virulence factors for pathogens like Yersinia pestis, the causative agent of plague. This technique helps in differentiating encapsulated bacteria from non-encapsulated ones. Spore formation (B), acid resistance (C), and alkali resistance (D) are not properties that can be identified using the Burri-Gins technique, making them incorrect choices.

Correct Answer: C

Rationale: The correct answer is C: ECHO virus infection. ECHO virus is transmitted via the fecal-oral route, meaning the virus is passed from feces to the mouth. This transmission occurs through contaminated food, water, or surfaces. Relapsed fever and spotted fever are generally transmitted by arthropod vectors like ticks. Pertussis, also known as whooping cough, spreads through respiratory droplets. Therefore, the fecal-oral route is not applicable to these diseases.

Correct Answer: D

Rationale: The correct answer is D: active transport system. Permeases are specific carriers that actively transport molecules across a cell membrane against their concentration gradient, requiring energy input. This process is known as active transport, which is essential for maintaining cellular homeostasis and allowing the cell to accumulate specific molecules. Facilitated diffusion (A) and passive transport (B) both involve the movement of molecules down their concentration gradient without the need for energy input. Simple diffusion (C) also does not involve specific carriers and relies on the natural movement of molecules from areas of high concentration to low concentration. Therefore, the correct choice is D as permeases specifically function in active transport systems.

Correct Answer: D

Rationale: The correct answer is D. Staphylococcus aureus, Escherichia coli, and Clostridium difficile are all known for causing hospital-acquired infections. Staphylococcus aureus can cause skin infections and pneumonia. Escherichia coli can lead to urinary tract infections. Clostridium difficile is associated with gastrointestinal infections. Each of these bacteria has been linked to healthcare-associated infections due to their ability to spread in healthcare settings. Therefore, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually is known to cause hospital-acquired infections.

Correct Answer: B

Rationale: The correct answer is B: CDC. The Centers for Disease Control and Prevention (CDC) is responsible for establishing hand-washing guidelines in healthcare settings to prevent infections. CDC is a leading authority in public health and provides evidence-based recommendations. OSHA (A) focuses on workplace safety, NIAD (C) is not a recognized organization, and WHO (D) provides global health guidelines but CDC is the primary authority for hand hygiene in the US healthcare system.

Correct Answer: D

Rationale: The correct answer is D. Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae are all known to cause meningitis. Neisseria meningitidis is a common cause of bacterial meningitis in young adults. Haemophilus influenzae is a leading cause of meningitis in children, and Streptococcus pneumoniae is a common cause in adults. Therefore, all three bacteria are responsible for causing meningitis, making option D the correct choice. Option A, B, and C are incorrect because they each represent only one of the bacteria responsible for causing meningitis, while option D includes all three.

Correct Answer: A

Rationale: The correct answer is A: Clostridium tetani. The presence of Gram-positive rods with terminal spores resembling drumsticks indicates Clostridium tetani, the causative agent of tetanus. This bacterium forms spores at one end, giving it a drumstick appearance under the microscope. Clostridium perfringens (B) and Clostridium botulinum (D) do not have terminal spores. Bacillus anthracis (C) forms spores but typically appears as a square-ended or bamboo stick shape. Therefore, based on the microscopy findings, Clostridium tetani is the most likely microorganism responsible for the wound infection.