ATI RN
Pediatric Immunization Test Questions Questions
Question 1 of 5
During the development of B cells, the Ig gene segments are rearranged and brought next to each other to form a contiguous functional gene (somatic recombination). The complex of enzymes involved in somatic recombination in lymphocytes is called:
Correct Answer: C
Rationale: V(D)J-recombinase, including RAG-1 and RAG-2, facilitates somatic recombination in B and T cells.
Question 2 of 5
The process used to increase antigen binding affinity is called somatic and occurs in cells but not cells.
Correct Answer: C
Rationale: Somatic hypermutation increases affinity in B cells but not in T cells.
Question 3 of 5
Co-receptor molecule involved in signal transduction
Correct Answer: C
Rationale: CD4 and CD8 are co-receptors that enhance signal transduction in T cells.
Question 4 of 5
How many genes does MHC class II have?
Correct Answer: D
Rationale: MHC class II includes six genes: HLA-DP, DQ, and DR, each with alpha and beta chains.
Question 5 of 5
Insulin-dependent diabetes mellitus
Correct Answer: D
Rationale: Insulin-dependent diabetes mellitus is associated with HLA-DR4.