During negative selection, a strong interaction between an immature T cell receptor and self-peptide:

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Lymphatic System Review Questions Questions

Question 1 of 5

During negative selection, a strong interaction between an immature T cell receptor and self-peptide:

Correct Answer: D

Rationale: Strong binding triggers apoptosis to eliminate autoreactive T cells, not rescue or migration.

Question 2 of 5

Which of the following bind to mast cells and cross-link, resulting in degranulation and release of histamine?

Correct Answer: C

Rationale: IgE binds mast cells for histamine release; IgM , IgA , IgG , and interleukins don't.

Question 3 of 5

Cell-mediated immunity is carried out by_____________ while humoral immunity is mainly carried out by________

Correct Answer: C

Rationale: T cells drive cell-mediated, B cells humoral immunity; not reversed or others (B, D).

Question 4 of 5

In an antigen haptens are:

Correct Answer: B

Rationale: Haptens are non-immunogenic alone, needing carriers; not inherently immunogenic .

Question 5 of 5

B and T cells are produced by stem cells that are formed in:

Correct Answer: A

Rationale: The early development of stem cell takes place in primitive tissue, late development in fetal liver and final development in bone marrow, making bone marrow the primary site.

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