During B cell development, when is there rearrangement in the heavy (H) chain of the immunoblobulin gene started?

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Pediatric Immunization NCLEX Questions Quizlet Questions

Question 1 of 5

During B cell development, when is there rearrangement in the heavy (H) chain of the immunoblobulin gene started?

Correct Answer: A

Rationale: Heavy chain rearrangement begins in the pro-B cell stage.

Question 2 of 5

At what stage does selection occur and where in the thymus does it occur?

Correct Answer: B

Rationale: Selection (positive and negative) occurs at the DP stage in the thymus cortex.

Question 3 of 5

In contrast toαβ T cells, γδ T cells recognize certain peptide and nonpeptide antigens ___ processing and in the ___ of MHC class I and/or II molecules.

Correct Answer: C

Rationale: γδ T cells recognize antigens without processing and independent of MHC molecules.

Question 4 of 5

Which of the following is NOT true when comparing primary immune response to subsequent (secondary) immune response?

Correct Answer: D

Rationale: Secondary response typically features IgG, not IgH (a typo for IgA/IgE), as the major class.

Question 5 of 5

Which of the following is a function of the adaptive immune system and NOT the innate immune system?

Correct Answer: A

Rationale: Distinguishing self from non-self is adaptive (e.g., T/B cell receptors), not innate.

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