During a routine physical examination, a solitary thyroid nodule is palpated in asymptomatic 10-year-old child. Of the following, the MOST likely cause is

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Pediatric Endocrine System Questions

Question 1 of 5

During a routine physical examination, a solitary thyroid nodule is palpated in asymptomatic 10-year-old child. Of the following, the MOST likely cause is

Correct Answer: B

Rationale: In children, a solitary thyroid nodule is most often a benign adenoma (B); carcinoma (A) is rarer.

Question 2 of 5

Precocious puberty in girls is defined by the onset of secondary sexual characteristics before the age of

Correct Answer: B

Rationale: Precocious puberty in girls is defined as onset before age 8 (B), per endocrine guidelines.

Question 3 of 5

The thyroid hormones are transported in plasma bound to thyroxine-binding globulin (TBG), a glycoprotein synthesized in the liver. TBG binds approximately 70% of T4 and 50% of T3. TBG level increase with administration of

Correct Answer: A

Rationale: Estrogens (A) increase TBG levels, raising bound thyroid hormone.

Question 4 of 5

Levothyroxine (I-T4) given orally is the treatment of choice in congenital hypothyroidism. The recommended initial starting dose is

Correct Answer: D

Rationale: Initial dose for congenital hypothyroidism is 10-15 μg/kg/day (E) to normalize T4 quickly.

Question 5 of 5

Chronic lymphocytic thyroiditis is the most common cause of acquired hypothyroidism, with or without goiter. All the following are true EXCEPT

Correct Answer: D

Rationale: The clinical course of chronic lymphocytic thyroiditis (Hashimoto’s) varies (not constant, D), with remission and progression possible.

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