Drugs are excreted from the body primarily via the:

Correct Answer: B

Rationale: The correct answer is B: kidneys. The kidneys are the primary organs responsible for excreting drugs from the body through urine. They filter the blood and remove waste products, including drugs, through the process of urine formation. The lungs primarily excrete gases and volatile substances, not drugs. The small intestines are mainly involved in absorption of nutrients, not drug excretion. The spleen is part of the immune system and does not play a direct role in drug excretion.

Correct Answer: C

Rationale: The correct answer is C: Leishmaniasis. The description of thin microorganisms with 12-14 uniform tendrils, 10-13 micrometers in length, and pale pink color matches the characteristics of Leishmania parasites seen in Giemsa-stained samples. Leishmania parasites are known to have a distinctive appearance with pointed tips and a specific size range. Syphilis (choice A) is caused by Treponema pallidum, which appears as tightly coiled spirochetes, not tendrils. Trypanosomiasis (choice B) is caused by Trypanosoma parasites, which have a different morphology and staining pattern. Relapsing fever (choice D) is caused by Borrelia recurrentis, which does not match the description given. Therefore, the correct choice is C as the description aligns closely with the characteristic features of Leishmania parasites.

Correct Answer: A

Rationale: The correct answer is A: Helicobacter pylori. This bacterium is a major cause of gastric ulcers by disrupting the balance between aggressive (acid, pepsin) and defensive (mucus, bicarbonate, prostaglandins) factors in the stomach lining. H. pylori infection leads to inflammation, weakening the protective mucosal barrier, making the stomach more susceptible to damage. Choices B, C, and D are defensive factors that help protect the stomach lining and prevent ulcer formation, so they do not contribute to the development of gastric ulcers.

Correct Answer: A

Rationale: Step-by-step rationale: 1. Purple-stained diplococci suggest Gram-positive cocci. 2. Capsule presence is a characteristic of Streptococcus pneumoniae. 3. S. pneumoniae is known to form diplococci arrangements. 4. Therefore, the microorganism most likely present is Streptococcus pneumoniae. Summary: - B: Klebsiella pneumoniae is a Gram-negative rod, not a cocci. - C: Neisseria meningitidis is a Gram-negative diplococcus, not a capsule producer. - D: Escherichia coli is a Gram-negative rod, not a cocci or capsule producer.

Correct Answer: A

Rationale: The correct answer is A: Lamblia. The presence of big pyriform cells with two nuclei in the duodenal contents indicates Giardia lamblia infection. This parasite is commonly found in contaminated water and causes symptoms like poor appetite and abdominal pain. Trichomonas, Amoeba, Trypanosoma, and Toxoplasma are not typically associated with these findings and symptoms. Therefore, Lamblia is the most likely microorganism based on the clinical presentation and microscopic examination results.

Correct Answer: C

Rationale: The correct answer is C (25°C) because dimorphic fungi typically grow as molds at lower temperatures. At 25°C, the fungus is likely in its mold phase, which is the preferred temperature range for mold growth. Choices A, B, and D are incorrect because 15°C and 20°C are too low for optimal mold growth, and 37°C is too high as it typically favors the yeast phase of dimorphic fungi. Therefore, the preferred temperature for mold growth of a dimorphic fungus is 25°C.

Correct Answer: B

Rationale: The correct answer is B because antigenic drift is not caused by the exchange of genetic information between animal and human influenza viruses. Antigenic drift is actually due to point mutations in the genes that encode for the surface proteins of the virus, leading to small changes in the antigens. These mutations can affect the hemagglutinin of both type A and B influenza viruses, making choices A and C correct. Choice D is incorrect because antigenic drift can occur in both type A and B influenza viruses, with type B being less prone to drift compared to type A.

Correct Answer: D

Rationale: The correct answer is D (All of the above) as all three bacteria (Escherichia coli, Salmonella enterica, Neisseria meningitidis) produce endotoxins causing fever and shock. Endotoxins are lipopolysaccharides found in the outer membrane of Gram-negative bacteria and can trigger an immune response leading to fever and shock. Escherichia coli and Salmonella enterica are common causes of food poisoning and sepsis, while Neisseria meningitidis is responsible for meningococcal meningitis and septicemia. Therefore, all three choices are correct in producing endotoxins that can cause fever and shock.

Correct Answer: A

Rationale: Passive immunity is the transfer of pre-formed antibodies from one individual to another, providing immediate protection. This process does not involve the recipient's immune response, hence it is called passive. Active immunity, on the other hand, involves the individual's immune system producing its own antibodies after exposure to an antigen. Innate immunity refers to the body's natural defense mechanisms present from birth, not involving antibodies. Therefore, the correct answer is A: passive immunity.