ATI RN
Advanced Pharmacology Across the Lifespan Questions
Question 1 of 5
Dose response data was collected during the preclinical testing of four drugs for the treatment of acute heart failure. Which drug studied was the most efficacious?
Correct Answer: A
Rationale: The correct answer is Drug A because it showed the highest efficacy in the dose-response data collected during preclinical testing. Efficacy refers to the ability of a drug to produce a desired therapeutic effect. In this case, Drug A demonstrated the most significant positive response in treating acute heart failure compared to Drugs B, C, and D. The other choices are incorrect because they did not exhibit the same level of efficacy as Drug A based on the data collected. Drug B, C, and D may have shown some effectiveness, but Drug A outperformed them in terms of efficacy for the treatment of acute heart failure.
Question 2 of 5
A59-year-old man with a body mass index of 42 and a long history of poorly controlled hypertension was recently diagnosed with migraine headaches. Which of the following anti-migraine drugs would be contraindicated in this patient?
Correct Answer: C
Rationale: The correct answer is C: Ergotamine. In this case, ergotamine is contraindicated due to the patient's poorly controlled hypertension. Ergotamine can cause vasoconstriction, potentially worsening hypertension and increasing the risk of cardiovascular events. Aspirin (A), acetaminophen (B), and ibuprofen (D) are safer options for migraine treatment in this patient as they do not have significant vasoconstrictive effects and are less likely to exacerbate hypertension.
Question 3 of 5
A54-year-old man at a scheduled ophthalmic check-up was found to have increased intraocular pressure. The man had been suffering from open-angle glaucoma for 2 years, but up until the current visit, the disease was found to be well controlled by local treatment with timolol and latanoprost. Drugs taken recently by the patient included over-the-counter preparations for episodic headache, heartburn, and insomnia. Which of the following drugs could have caused the patient's increased intraocular pressure?
Correct Answer: D
Rationale: The correct answer is D: Diphenhydramine. Diphenhydramine is an anticholinergic drug that can cause an increase in intraocular pressure by dilating the pupil and affecting the eye's ability to drain fluid properly. The patient's increased intraocular pressure could be due to the use of diphenhydramine for insomnia. Acetaminophen (A), omeprazole (B), and ibuprofen (C) do not typically cause an increase in intraocular pressure. Acetaminophen is a pain reliever, omeprazole is a proton pump inhibitor used for heartburn, and ibuprofen is a nonsteroidal anti-inflammatory drug.
Question 4 of 5
A hydrophilic medicinal agent has the following property:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Most of drugs are distributed homogeneously.
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.