ATI RN
openstax microbiology test bank Questions
Question 1 of 9
DNA transfer from one bacterium to another through phages is termed as:
Correct Answer: B
Rationale: The correct answer is B: Transduction. In bacterial genetics, transduction refers to the process of DNA transfer from one bacterium to another via bacteriophages. During transduction, the bacteriophage infects a bacterium, incorporating bacterial DNA into its own genome, which is then transferred to another bacterium upon infecting it. Rationale: A: Transfection is the process of introducing foreign DNA into eukaryotic cells, not bacteria. C: Induction is the process of activating gene expression in a cell. D: Infection is a general term for the invasion of pathogens into a host organism, not specific to DNA transfer via phages in bacteria.
Question 2 of 9
Which of the following bacteria is responsible for causing the disease known as syphilis?
Correct Answer: A
Rationale: The correct answer is A: Treponema pallidum. This bacterium is responsible for causing syphilis due to its unique spiral shape and ability to penetrate mucous membranes. It is transmitted through sexual contact or from mother to child during childbirth. Neisseria gonorrhoeae causes gonorrhea, Chlamydia trachomatis causes chlamydia, and Escherichia coli is a common bacterium found in the gut. Therefore, they are not responsible for syphilis.
Question 3 of 9
Which of the following is a type of acute infection generally caused by group A Streptococcus?
Correct Answer: C
Rationale: The correct answer is C: Erysipelas. Erysipelas is a type of acute infection caused by group A Streptococcus bacteria. This bacteria infects the upper dermis and superficial lymphatics, leading to a distinct raised, well-demarcated, erythematous skin lesion. The other choices are incorrect because: A Carbuncle is a deep skin infection involving hair follicles, B Impetigo is a superficial skin infection caused by Staphylococcus or Streptococcus bacteria, and D Acne is a chronic inflammatory skin condition not typically caused by group A Streptococcus.
Question 4 of 9
The most common test for the diagnosis of Lyme borreliosis is:
Correct Answer: C
Rationale: The correct answer is C: ELISA, Western blot. These tests are commonly used for diagnosing Lyme borreliosis due to their high sensitivity and specificity in detecting antibodies against Borrelia burgdorferi, the causative agent. ELISA is the initial screening test, while Western blot is used for confirmation. Widal agglutination test (A) is used for diagnosing typhoid fever, not Lyme disease. Cultivation on blood and chocolate agar (B) is not commonly used for diagnosing Lyme borreliosis as Borrelia species are difficult to culture. Ascoli thermoprecipitation test (D) is used for diagnosing pneumonia caused by Streptococcus pneumoniae, not Lyme disease.
Question 5 of 9
What is the main component of bacterial cell walls?
Correct Answer: C
Rationale: The correct answer is C: Peptidoglycan. Bacterial cell walls are primarily composed of peptidoglycan, a unique molecule consisting of alternating sugar chains connected by peptide cross-links. This structure provides rigidity and shape to the cell wall, protecting the bacterial cell from osmotic pressure. Lipopolysaccharides (A) are found in the outer membrane of Gram-negative bacteria. Cellulose (B) is a component of plant cell walls, not bacterial cell walls. Chitin (D) is a polysaccharide found in the exoskeletons of arthropods and fungi, not in bacterial cell walls.
Question 6 of 9
A patient suffers from pulmonary tuberculosis. During treatment neuritis of visual nerve arose. What drug has caused this by-effect?
Correct Answer: B
Rationale: The correct answer is B: Ethambutol. Ethambutol is known to cause optic neuritis, affecting the visual nerve. It is a well-documented side effect of this drug. Isoniazid (Choice A) is associated with peripheral neuropathy, not optic neuritis. Kanamycin (Choice C) is known for its side effects on the inner ear, causing hearing loss. Rifampicin (Choice D) is not typically associated with optic neuritis but can cause other adverse effects like hepatitis. By process of elimination and knowledge of drug side effects, Ethambutol is the most likely culprit.
Question 7 of 9
A patient with bacterial endocarditis had Gram-positive cocci in chains isolated from blood cultures. The organism was catalase-negative. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes. This is because Streptococcus pyogenes is a Gram-positive cocci in chains bacterium that is catalase-negative, making it the most likely causative agent in this scenario. Streptococcus pyogenes is a common pathogen causing bacterial endocarditis. Summary of other choices: B: Staphylococcus aureus is a Gram-positive cocci bacterium but is catalase-positive, so it is unlikely in this case. C: Enterococcus faecalis is a Gram-positive cocci bacterium, but it is catalase-negative, which is not consistent with the given information. D: Micrococcus luteus is a Gram-positive cocci bacterium but is catalase-positive, making it an unlikely causative agent.
Question 8 of 9
Bacteria associated with hospital-acquired infections:
Correct Answer: B
Rationale: The correct answer is B: Pseudomonas aeruginosa. This bacterium is commonly associated with hospital-acquired infections due to its ability to survive in hospital environments, resist antibiotics, and infect immunocompromised patients. Streptococcus pneumoniae (choice A) is more commonly associated with community-acquired pneumonia. Vibrio cholerae (choice C) causes cholera, a waterborne disease, and is not typically associated with hospital-acquired infections. Choice D is incorrect because Pseudomonas aeruginosa is indeed associated with hospital-acquired infections.
Question 9 of 9
The ability of Clostridium tetani to produce exotoxins is encoded by?
Correct Answer: C
Rationale: The correct answer is C: genes with plasmid location. Clostridium tetani produces exotoxins through genes located on plasmids. Plasmids are extrachromosomal genetic elements that carry additional genes. These genes encode for the production of exotoxins in Clostridium tetani. Choices A, B, and D are incorrect because Clostridium tetani does produce exotoxins, it does not have only endotoxin activity, and the genes responsible for exotoxin production are located on plasmids, not solely on the chromosome or both chromosome and plasmid.