DNA microarrays and human genome data are being us

ATI RN

ATI RN Test Bank

DNA microarrays and human genome data are being used to diagnose and manage cancer:

A. TRUE B. FALSE C. D.

Correct Answer: A

Rationale: True. Microarrays and genomic data help identify cancer mutations and guide treatment.

The characteristic indicated by the blackened figures is probably:

A. Dominant B. Recessive C. Non-dominant D. Sex-linked recessive

Correct Answer: A

Rationale: Without the pedigree, dominant is assumed if blackened figures appear in every generation; recessive if skipping generations.

Consanguinity shows a strong association with which pattern of inheritance?

A. Autosomal dominant B. Autosomal recessive C. X-linked dominant D. X-linked recessive

Correct Answer: B

Rationale: Consanguinity increases the risk of autosomal recessive disorders due to shared rare alleles.

Large triplet repeat expansions can be detected by:

A. Polymerase chain reaction B. Single strand conformational polymorphism analysis C. Southern blotting D. Western blotting

Correct Answer: C

Rationale: Southern blotting is used for large repeat expansions (e.g., Huntington’s), as PCR may fail with very large repeats.

The DiGeorge/Shprintzen syndrome is caused by a deletion in which chromosome?

A. 4 B. 7 C. 15 D. 22

Correct Answer: D

Rationale: DiGeorge syndrome (22q11.2 deletion) affects chromosome 22.

$89/ 30 days

$150/ 90 days