Disturbance of vitamin K-dependent clotting function is associated with:

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Question 1 of 5

Disturbance of vitamin K-dependent clotting function is associated with:

Correct Answer: A

Rationale: Cefamandole can interfere with vitamin K-dependent clotting, increasing bleeding risk.

Question 2 of 5

A 39-year-old man with aortic insufficiency and a history of multiple antibiotic resistances is given a prophylactic intravenous dose of antibiotic before surgery to insert a prosthetic heart valve. As the antibiotic is being infused, the patient becomes flushed over most of his body. Which of the following antibiotics is most likely responsible?

Correct Answer: D

Rationale: Vancomycin infusion can cause 'red man syndrome,' characterized by flushing.

Question 3 of 5

A 35-year-old woman complains of itching in the vulval area. Hanging-drop examination of the urine reveals trichomonas. Which of the following is the preferred treatment for the trichomoniasis?

Correct Answer: C

Rationale: Metronidazole is the preferred treatment for trichomoniasis.

Question 4 of 5

A jaundiced 1-day-old premature infant with elevated free bilirubin is seen in the premature baby nursery. The mother had received an antibiotic combination for a urinary tract infection (UTI) 1 week before delivery. Which of the following is the most likely cause of the baby's kernicterus?

Correct Answer: D

Rationale: Sulfonamides displace bilirubin from albumin, causing kernicterus in neonates.

Question 5 of 5

Which is NOT an advantage of dalteparin over unfractionated heparin?

Correct Answer: D

Rationale: Dalteparin (a low-molecular-weight heparin) has greater bioavailability, less thrombocytopenia risk, and a longer half-life than unfractionated heparin, but greater efficacy is not a consistent advantage, as it depends on the condition treated.

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