ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
Digeorge syndrome is known to increase likelihood of infection of some microbes, why is that?
Correct Answer: B
Rationale: DiGeorge syndrome impairs thymus development, reducing T cell production.
Question 2 of 5
All the following are features of ataxia-telangiectasia EXCEPT
Correct Answer: A
Rationale: Ataxia-telangiectasia involves neurologic decline, malignancies, and sinopulmonary infections, but hepatic manifestations are not a typical feature.
Question 3 of 5
A 4-year-old boy presented with high fever, decreased appetite, aphthous stomatitis, and cellulitis of the right calf muscle. His absolute neutrophil count (ANC) was 600/μL. The MOST likely organisms causing this condition are
Correct Answer: D
Rationale: Neutropenia predisposes to bacterial infections; Staphylococcus aureus and gram-negative bacteria (e.g., Pseudomonas) are common culprits in cellulitis and stomatitis.
Question 4 of 5
In patient with Chédiak-Higashi syndrome, the only curative therapy is hematopoietic stem cell transplantation which correct all the following EXCEPT
Correct Answer: A
Rationale: HSCT corrects immune and hematologic defects in Chédiak-Higashi but not progressive neuropathy, which is neurologic in origin.
Question 5 of 5
The immune system uses as well as molecules (e.g. complement components). The immune system uses as well as antigen recognition molecules.
Correct Answer: B
Rationale: The immune system has two main branches: innate and adaptive. Innate immunity uses phagocytes (e.g., macrophages) as cells and complement components as molecules, while adaptive immunity uses lymphocytes (e.g., T and B cells) and antigen recognition molecules (e.g., antibodies, T-cell receptors).