ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Diethylstilbestrol (DES) should never be used in pregnant women because it is associated with all of the following EXCEPT:
Correct Answer: A
Rationale: DES, a synthetic estrogen, causes deep vein thrombosis (choice A), feminization of male offspring (choice B), and miscarriages (choice C) in pregnancy, linked to historical congenital anomalies (e.g., vaginal adenocarcinoma). Virilization of female offspring (choice D) isn't reported; DES mimics estrogen, not androgens. This exception highlights its teratogenic risks, banning its use in pregnancy.
Question 2 of 5
In the treatment of congenital adrenal hyperplasia in which there is excess production of cortisol precursor, the purpose of administration of synthetic glucocorticoid is:
Correct Answer: D
Rationale: In CAH (choice D), synthetic glucocorticoids suppress ACTH, reducing adrenal precursor excess (e.g., 17-hydroxyprogesterone). Aldosterone (choice A), renal (choice B), and immune (choice C) effects aren't primary goals. ACTH suppression corrects the defect.
Question 3 of 5
An action common to most general anesthetics
Correct Answer: C
Rationale: Many general anesthetics inhibit glutamate (excitatory neurotransmitter) to produce sedation and anesthesia.
Question 4 of 5
A patient is brought to the emergency room suffering from an overdose of an illicit drug. She is agitated, has disordered thought processes, suffers from paranoia, and hears voices. The drug most likely to be responsible for her condition is
Correct Answer: C
Rationale: Methamphetamine toxicity causes hallucinations, paranoia, and agitation due to increased dopamine activity.
Question 5 of 5
Epinephrine added to a solution of lidocaine for a peripheral nerve block will
Correct Answer: B
Rationale: Epinephrine causes vasoconstriction, reducing systemic absorption and prolonging the duration of the local anesthetic effect.