Diabetic ketoacidosis (DKA) is the end result of the metabolic abnormalities resulting from a severe deficiency of insulin or insulin effectiveness. DKA is characterized by the following EXCEPT

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Pediatric Endocrine Nursing Questions Questions

Question 1 of 5

Diabetic ketoacidosis (DKA) is the end result of the metabolic abnormalities resulting from a severe deficiency of insulin or insulin effectiveness. DKA is characterized by the following EXCEPT

Correct Answer: B

Rationale: DKA features an elevated anion gap (not normal, B) due to ketoacidosis.

Question 2 of 5

The MOST commonly used and the only FDA-approved oral agent for the treatment of T2 DM in children and adolescents is

Correct Answer: C

Rationale: Metformin (C) is the only FDA-approved oral agent for pediatric T2DM.

Question 3 of 5

Inborn errors of metabolism (IEM) are hereditary biochemical disorders caused by single-gene mutations that encode specific proteins. The following are the common characteristics of IEM EXCEPT

Correct Answer: B

Rationale: Most IEMs are autosomal recessive (A), require early diagnosis (C), present after birth (D), and vary in severity (E). However, later symptom onset often indicates milder disease, not greater severity, making B the exception.

Question 4 of 5

A 5-year-old mentally retarded girl presented with repeated convulsions and abnormal EEG finding. On examination, she had a light skin, small head, and exaggerated reflexes. Of the following, the MOST appropriate method to confirm the diagnosis is

Correct Answer: D

Rationale: Plasma phenylalanine concentration confirms PKU in this classic presentation (mental retardation, seizures, light skin, microcephaly), offering definitive diagnosis over screening (A, C) or secondary tests (D). Flow cytometry (B) is unrelated.

Question 5 of 5

The MOST appropriate method to confirm the diagnosis of tyrosinemia type 1 is by elevated level of

Correct Answer: D

Rationale: Serum succinylacetone is the specific diagnostic marker for tyrosinemia type 1, reflecting fumarylacetoacetate hydrolase deficiency, more definitive than α-fetoprotein (A), tyrosine (B), methionine (C), or ALA (E).

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