ATI RN
Pediatric Immunization NCLEX Questions Ricci Questions
Question 1 of 5
Deletions in the T-cell CD154 (CD40L) gene produce?
Correct Answer: A
Rationale: CD40L deficiency prevents class switching from IgM to other isotypes, resulting in hyper-IgM syndrome.
Question 2 of 5
An epitope...?
Correct Answer: A
Rationale: An epitope is the specific region on an antigen recognized and bound by an antibody.
Question 3 of 5
Neutropenia is noted in children in all of the following conditions EXCEPT
Correct Answer: D
Rationale: Hunter syndrome (MPS II) is a lysosomal storage disorder not typically associated with neutropenia. Kostmann disease (severe congenital neutropenia), viral infections, and maternal preeclampsia can all cause neutropenia through various mechanisms affecting neutrophil production or survival.
Question 4 of 5
Matching: Immunodeficiency - May be confused with AIDS
Correct Answer: D
Rationale: CD8 lymphocytopenia can mimic AIDS due to low CD8 T-cell counts, leading to opportunistic infections similar to HIV.
Question 5 of 5
A child is found to have a normal WBC count but serum concentrations of IgG, IgA, IgM, and IgE below the 95% lower limits for age. Which is the most likely diagnosis?
Correct Answer: D
Rationale: Common variable immunodeficiency (CVID) is characterized by low levels of multiple immunoglobulin classes (IgG, IgA, IgM) with normal WBC, often presenting later in childhood.