ATI RN
ATI Pharmacology The Respiratory System Quizlet Questions
Question 1 of 5
Deficiencies in cyanocobalamin (B12) can result in
Correct Answer: B
Rationale: Cyanocobalamin, or vitamin B12, is essential for red blood cell production and neurological function, and its deficiency directly leads to pernicious anemia, a condition characterized by large, immature red blood cells due to impaired DNA synthesis. This occurs because B12 is crucial for folate metabolism and erythropoiesis, and without it, anemia develops, often accompanied by neurological symptoms like numbness or tingling. Pellagra, however, results from niacin (vitamin B3) deficiency, manifesting as dermatitis, diarrhea, and dementia-unrelated to B12's role. Rickets stems from vitamin D deficiency, causing bone deformities due to poor calcium absorption, not a B12 issue. Scurvy arises from vitamin C deficiency, leading to collagen breakdown and symptoms like bleeding gums, distinct from B12's hematological effects. Pernicious anemia stands out as the correct outcome because B12 deficiency disrupts bone marrow function, and it often requires pharmacotherapy, such as B12 injections, especially if absorption is impaired (e.g., due to lack of intrinsic factor). This specificity eliminates other conditions, highlighting B12's unique role in blood and nerve health.
Question 2 of 5
A patient taking isoniazid is worried about the negative effects of the drug. The nurse provides information knowing that which is an adverse effect of the drug?
Correct Answer: B
Rationale: Isoniazid is associated with hepatotoxicity, which can range from asymptomatic elevation of liver enzymes to severe hepatitis. Patients should be monitored for symptoms such as fatigue, nausea, and jaundice. Ototoxicity and nephrotoxicity are not common adverse effects of isoniazid. Optic neuritis is a rare side effect of ethambutol, another antitubercular drug, not isoniazid.
Question 3 of 5
In Fried's rule of dosage calculation, it is the number of months a child has reached an age when an adult dose can be tolerated>
Correct Answer: C
Rationale: In Fried's rule for dosage calculation, the formula is to divide the child's age in months by 150 to find the fraction of adult dose that can be tolerated. Generally, a child is considered to tolerate an adult dose when they have reached 12 months of age. This is based on the assumption that a 12-month-old child can typically tolerate a dose similar to that of an adult. Therefore, the correct answer is 12 months, which is option C.
Question 4 of 5
The client receives estrogen for prostate cancer. He asks the nurse why he is receiving a female hormone. What is the best response by the nurse?
Correct Answer: C
Rationale: Prostate cancer is androgen-dependent, relying on testosterone and other androgens for growth. Estrogen therapy suppresses pituitary secretion of luteinizing hormone, reducing testicular androgen production, effectively starving the cancer. This hormonal manipulation is a standard approach. Choice A inaccurately suggests direct cell death, not estrogen's mechanism. Choice B overstates testosterone elimination; it's reduced, not eradicated. Choice D misattributes nutrient blockade, unrelated to estrogen's action. The nurse's best response (C) clarifies estrogen's role in androgen suppression, addressing the client's confusion with precision and relevance to his treatment.
Question 5 of 5
A patient with diabetes has a new prescription for the ACE inhibitor lisinopril. She questions this order because her physician has never told her that she has hypertension. What is the best explanation for this order?
Correct Answer: D
Rationale: The best explanation for the prescription of the ACE inhibitor lisinopril for a patient with diabetes who does not have hypertension is that this medication has a protective effect on the kidneys for patients with diabetes. ACE inhibitors like lisinopril have been shown to have renal protective benefits by reducing the progression of diabetic nephropathy, a common complication of diabetes that affects the kidneys. Therefore, even in the absence of hypertension, using an ACE inhibitor like lisinopril can help preserve kidney function in patients with diabetes.