ATI RN
ATI Pharmacology Study Guide Questions
Question 1 of 5
Deficiencies in cyanocobalamin (B12) can result in
Correct Answer: B
Rationale: Cyanocobalamin, or vitamin B12, is essential for red blood cell production and neurological function, and its deficiency directly leads to pernicious anemia, a condition characterized by large, immature red blood cells due to impaired DNA synthesis. This occurs because B12 is crucial for folate metabolism and erythropoiesis, and without it, anemia develops, often accompanied by neurological symptoms like numbness or tingling. Pellagra, however, results from niacin (vitamin B3) deficiency, manifesting as dermatitis, diarrhea, and dementia-unrelated to B12's role. Rickets stems from vitamin D deficiency, causing bone deformities due to poor calcium absorption, not a B12 issue. Scurvy arises from vitamin C deficiency, leading to collagen breakdown and symptoms like bleeding gums, distinct from B12's hematological effects. Pernicious anemia stands out as the correct outcome because B12 deficiency disrupts bone marrow function, and it often requires pharmacotherapy, such as B12 injections, especially if absorption is impaired (e.g., due to lack of intrinsic factor). This specificity eliminates other conditions, highlighting B12's unique role in blood and nerve health.
Question 2 of 5
The nurse works with a physician who frequently prescribes benzodiazepines. The use of benzodiazepines in which patient would cause the nurse the most concern?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
An important function of calcium is to
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A 6-year-old boy cuts his hand on the training wheel of his bicycle. The wound is 1.5 cm in size and the bleeding stops with direct pressure. One of the steps of blood clotting involved platelet aggregation through activation of collagen. Platelet release of granules is mediated by the release of mediators. Which of the following mediators, if activated, will likely cause bleeding to continue?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
A 28-year-old female presents with a 4 × 5 cm purulent ulcer on her abdomen following a spider bite. A wound culture grows MRSA, so intravenous vancomycin is started. While receiving her first dose of vancomycin, her face, neck, and chest flushed red. This reaction can best be described as
Correct Answer: A
Rationale: Vancomycin's red man syndrome-flushing during infusion-is non-hypersensitivity mast cell degranulation . Rapid infusion triggers histamine release, not IgE-mediated allergy . Type II , III , and IV (E) involve immune mechanisms unrelated to this acute, rate-dependent reaction. Slowing infusion prevents it, distinguishing it from true hypersensitivity, aligning with vancomycin's pharmacology in MRSA treatment.