ATI RN
Pediatric Immunizations NCLEX Questions Questions
Question 1 of 5
Defects in Macrophage to kill bacteria that synthesis Catalase; this called?
Correct Answer: A
Rationale: Chronic granulomatous disease results from defective NADPH oxidase, impairing macrophages' ability to kill catalase-producing bacteria.
Question 2 of 5
Matching: Immunodeficiency - High frequency of autoimmune disorders
Correct Answer: C
Rationale: CVID is associated with a high frequency of autoimmune disorders due to immune dysregulation.
Question 3 of 5
The X-linked lymphoproliferative (XLP) syndrome is classically associated with overwhelming infection with which organism?
Correct Answer: A
Rationale: XLP is classically linked to severe, often fatal Epstein-Barr virus infections due to defective immune regulation.
Question 4 of 5
Repeated meningococcal infections suggest what type of immune disorder?
Correct Answer: D
Rationale: Repeated meningococcal infections suggest a complement deficiency, particularly terminal components (C5-9), impairing bacterial lysis.
Question 5 of 5
An 8-month-old infant presented with chronic diarrhea, persistent right ear discharge, oral candidiasis responding poorly to antifungal drugs, and failure to thrive. On examination the infant has exfoliative erythroderma, lymphadenopathy, and hepatosplenomegaly. Peripheral blood showed eosinophilia and elevated IgE. The parents are young first cousin and he is their first baby. Of the following, the MOST likely diagnosis is
Correct Answer: C
Rationale: Omenn syndrome, a form of SCID, presents with erythroderma, eosinophilia, and elevated IgE due to consanguinity-related genetic defects.