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Drugs Affecting the Female Reproductive System NCLEX Quizlet Questions
Question 1 of 5
Danazol produces the following side effects in premenopausal women except:
Correct Answer: D
Rationale: The correct answer is D: Hot flashes. Danazol is a synthetic androgen that suppresses ovarian function, leading to amenorrhea and decreased estrogen levels. This mechanism of action makes it unlikely to cause hot flashes, which are commonly associated with estrogen fluctuations. Acne (Choice A), menorrhagia (Choice B), and amenorrhea (Choice C) are potential side effects of Danazol due to its hormonal effects on the body.
Question 2 of 5
Estrogen therapy in postmenopausal women has been implicated in increasing the risk of the following disorders except:
Correct Answer: B
Rationale: Estrogen therapy in postmenopausal women decreases the risk of osteoporosis by preserving bone density. Estrogen deficiency after menopause is a major risk factor for osteoporosis. The increased risk of gall stones, endometrial carcinoma, and breast cancer are associated with estrogen therapy due to its effects on bile composition, endometrial cell proliferation, and breast tissue growth, respectively. Therefore, the correct answer is B as estrogen therapy actually helps prevent osteoporosis in postmenopausal women.
Question 3 of 5
Estrogen therapy can worsen the following associated conditions except:
Correct Answer: B
Rationale: Estrogen therapy can worsen conditions that are sensitive to hormonal fluctuations. Cholelithiasis (gallstones) is not influenced by estrogen levels, so it is not worsened by estrogen therapy. Migraine, acne vulgaris, and endometriosis are conditions known to be affected by estrogen levels and can potentially worsen with estrogen therapy. Therefore, the correct answer is B. Migraine can worsen due to estrogen's impact on blood vessels, acne vulgaris can worsen due to increased sebum production, and endometriosis can worsen due to estrogen's role in promoting tissue growth.
Question 4 of 5
Select the compound which used for hormone replacement therapy in postmenopausal women serves the purpose of both estrogen and progestin with weak androgenic activity:
Correct Answer: A
Rationale: Rationale: 1. Tibolone is a compound used for hormone replacement therapy in postmenopausal women. 2. Tibolone serves the purpose of both estrogen and progestin. 3. It has weak androgenic activity, making it suitable for menopausal symptoms. 4. Mestranol is an estrogen-only compound, not suitable for progestin effects. 5. Desogestrel and Gestodene are progestins but do not have estrogenic properties. In summary, Tibolone is the correct choice as it combines estrogen and progestin with weak androgenic activity, unlike the other options.
Question 5 of 5
The following drug can cause rickets in children by interfering with vitamin D action:
Correct Answer: A
Rationale: The correct answer is A: Tetracycline. Tetracycline can cause rickets in children by binding to calcium in bones, inhibiting bone growth. This interference with vitamin D action leads to impaired calcium absorption. Digoxin, Phenytoin, and Ciprofloxacin do not interfere with vitamin D metabolism or calcium absorption, ruling them out as potential causes of rickets in children.