Cystic fibrosis is a genetic disorder of eccrine a

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Question 1 of 5

Cystic fibrosis is a genetic disorder of eccrine and exocrine gland function. All the following statements about cystic fibrosis are true EXCEPT

A. it is the most common genetic disease in whites in the U.S. B. it is inherited as an autosomal recessive trait C. about 1 in 20 whites are heterozygous for the gene D. the diagnosis can be confirmed by demonstrating an absence of chloride in the sweat

Correct Answer: D

Rationale: High sweat chloride confirms CF, not absence.

Question 2 of 5

The reasons for the poor 5-year survival rate for pancreatic cancer include all the following EXCEPT

A. the difficulty of establishing a diagnosis early during pathogenesis B. the usual ineffectiveness of radiotherapy C. the usual ineffectiveness of chemotherapy D. underlying diseases such as diabetes mellitus

Correct Answer: D

Rationale: Diabetes is a risk, not a survival factor; others limit prognosis.

Question 3 of 5

Prognosis in Hodgkin's disease correlates with all the following EXCEPT

A. the stage of disease at the time of diagnosis B. the presence of systemic symptoms C. the histologic type D. HLA type

Correct Answer: D

Rationale: HLA isn’t prognostic; others are.

Question 4 of 5

The development of mesothelioma is a dreaded consequence of exposure to asbestos. Asbestos-related mesothelioma is characterized by

A. a lifetime incidence of about 10 percent among persons with heavy exposure to asbestos B. an increased incidence in smokers C. an incidence that does not depend upon the type of asbestos fiber D. a mean latency of about 10 years after exposure

Correct Answer: A

Rationale: ~10% lifetime risk with heavy exposure; B (no synergy), C (fiber type matters), D (~30-40 years) false.

Question 5 of 5

Epidemiologic investigations of dementia have found

A. that more than 90 percent of patients in nursing homes are demented B. that it is the most common cause of death among nursing home residents C. that more than 10 million persons in the U.S. have Alzheimer's disease D. that there is an increased incidence of Alzheimer's disease among relatives of patients with that disease

Correct Answer: D

Rationale: Familial risk is true; A (~60-70%), B (CV disease), C (~6 million) false.

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Cystic fibrosis is a genetic disorder of eccrine and exocrine gland function. All the following statements about cystic fibrosis are true EXCEPT

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