Cortisol deficiency in congenital adrenal hyperpla

ATI RN

ATI RN Test Bank

Cortisol deficiency in congenital adrenal hyperplasia (salt wasting form of the disease) is treated with hydrocortisone

A. 5-10 mg/mÂ²/24 hr B. 10-15 mg/mÂ²/24 hr C. 15-20 mg/mÂ²/24 hr D. 20-25 mg/mÂ²/24 hr

Correct Answer: C

Rationale: Hydrocortisone dose for CAH is typically 15-20 mg/mÂ²/day (C) to replace cortisol.

Significant gynecomastia is seen in

A. hyperthyroidism B. Klinefelter syndrome C. 17-ketosteroid reductase deficiency D. 11Î²-hydroxylase deficiency

Correct Answer: B

Rationale: Klinefelter syndrome (B) commonly features significant gynecomastia due to hypogonadism.

Familial isolated gonadotropin deficiency associated with anosmia is

A. Noonan syndrome B. Bloom syndrome C. Werner syndrome D. Kallmann syndrome

Correct Answer: D

Rationale: Kallmann syndrome (D) features hypogonadotropic hypogonadism and anosmia.

Subjects with type 1 DM have evidence for celiac disease in

A. 5-10% B. 11-15% C. 16-20% D. 21-25%

Correct Answer: A

Rationale: 5-10% (A) of type 1 DM patients have celiac disease, per screening studies.

Nonketotic hyperosmolar coma is characterized by the following EXCEPT

A. severe hyperglycemia B. nonketotic acidosis C. severe dehydration D. hypothermia

Correct Answer: B

Rationale: Nonketotic hyperosmolar coma lacks acidosis (B); it features hyperglycemia (A) and dehydration (C).

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