Correct the statements concerning ketorolac include all of the following EXCEPT:

Correct Answer: C

Rationale: The correct answer is C because ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that does not have a high potential for physical dependence and abuse like opioids. A: It inhibits COX, reducing inflammation and pain. B: It is effective for short-term pain relief but is not as potent as morphine. D: It does not produce respiratory depression, which is a common side effect of opioids. In summary, C is incorrect as ketorolac is not associated with physical dependence and abuse, making it a safer option compared to opioids for pain management.

Correct Answer: C

Rationale: The correct answer is C: Hypotension. Caffeine is a stimulant that can increase blood pressure, so hypotension is not an adverse effect. A: Arrhythmias can occur due to caffeine's stimulant effects on the heart. B: Insomnia is a common side effect of caffeine due to its ability to disrupt sleep patterns. D: Psychomotor excitation can happen as caffeine increases alertness and arousal. Therefore, hypotension is the exception among the choices as it does not align with caffeine's typical effects on the body.

Correct Answer: B

Rationale: The correct answer is B: 7-10 days. Opioid withdrawal symptoms typically start within 6-12 hours after the last dose and peak around 2-3 days. The acute phase, marked by intense symptoms like anxiety, sweating, and insomnia, usually lasts about a week. After this period, symptoms gradually improve. Choices A, C, and D are incorrect. Choice A is too short for the acute phase. Choice C is too long, indicating the more prolonged post-acute withdrawal phase. Choice D is significantly longer and indicative of a chronic condition, not acute withdrawal.

Correct Answer: D

Rationale: The correct answer is D: Cytiton. The respiratory center is primarily stimulated by drugs that act on the central nervous system. Cytiton is not known to directly activate the respiratory center. Bemegride, caffeine, and aethymizole are central nervous system stimulants that can directly activate the respiratory center. Caffeine, for example, is a respiratory stimulant and can increase respiratory rate. Aethymizole is used to treat respiratory depression caused by opioid overdose. Bemegride is a respiratory stimulant used to treat respiratory depression. Therefore, D is the correct answer as it is not a drug known to directly activate the respiratory center.

Correct Answer: B

Rationale: The correct answer is B: Cisapride. Cisapride is a prokinetic agent that enhances gastrointestinal motility, therefore it does not reduce intestinal peristalsis. Loperamide (A) is an anti-diarrheal drug that acts by slowing down intestinal peristalsis. Methyl cellulose (C) is a bulk-forming laxative that can help regulate bowel movements by increasing stool bulk and promoting peristalsis. Magnesium aluminium silicate (D) is an antacid that can potentially slow down intestinal transit time by absorbing water in the intestine. So, B is the correct answer as it is the only drug that does not reduce intestinal peristalsis.