ATI RN
Cardiovascular Drugs Pharmacology PDF Questions
Question 1 of 5
Conjugation is:
Correct Answer: C
Rationale: Conjugation is the coupling of a drug with an endogenous substrate to facilitate its elimination from the body. This process involves the addition of specific molecules (such as glucuronic acid, sulfate, or amino acids) to the drug molecule, making it more water-soluble for easier excretion. Choice A is incorrect because conjugation does not involve drug reduction. Choice B is incorrect as conjugation does not involve drug oxidation. Choice D is incorrect as conjugation is not about solubilization in lipids but rather in water-soluble forms for excretion.
Question 2 of 5
The symptoms of mushroom poisoning include all of the following EXCEPT:
Correct Answer: B
Rationale: The correct answer is B because dryness of mouth, hyperpyrexia (high fever), and hallucination are not typical symptoms of mushroom poisoning. Salivation, lacrimation, nausea, vomiting (choice A), headache, abdominal colic (choice C), bradycardia, hypotension, and shock (choice D) are common symptoms seen in mushroom poisoning cases. Dry mouth, high fever, and hallucinations are more likely to be associated with other conditions or toxicities.
Question 3 of 5
Atropine may cause a rise in body temperature (atropine fever):
Correct Answer: C
Rationale: The correct answer is C because infants and children are more sensitive to atropine's effects, including the potential for causing a rise in body temperature. Atropine inhibits sweat gland function, leading to decreased ability to regulate body temperature, especially in pediatric populations. Choice A is incorrect because atropine fever can occur in adults as well. Choice B is incorrect because pregnancy status does not directly affect the likelihood of atropine-induced fever. Choice D is incorrect because not all adults experience atropine fever, while infants and children are more susceptible.
Question 4 of 5
Beta adrenoreceptor subtypes is contained in all of the following tissues EXCEPT:
Correct Answer: C
Rationale: The correct answer is C: Pupillary dilator muscle. Beta adrenoreceptor subtypes are found in bronchial muscles, heart, and fat cells, but not in pupillary dilator muscles. These receptors are involved in various functions such as bronchodilation, cardiac stimulation, and lipolysis. Pupillary dilator muscles are predominantly innervated by alpha adrenergic receptors, not beta adrenergic receptors, which regulate pupil constriction. Thus, the absence of beta adrenoreceptor subtypes in pupillary dilator muscles makes choice C the correct answer.
Question 5 of 5
Which of the following agents is an alfa2–selective antagonist?
Correct Answer: A
Rationale: The correct answer is A: Yohimbine. Yohimbine is an alpha2-selective antagonist because it specifically blocks alpha2-adrenergic receptors. This leads to increased sympathetic activity since alpha2 receptors normally inhibit sympathetic activity when activated. B: Tamsulosin is an alpha1-selective antagonist used to treat benign prostatic hyperplasia. C: Tolazoline is a non-selective alpha-adrenergic antagonist, affecting both alpha1 and alpha2 receptors. D: Prazosin is an alpha1-selective antagonist used to treat hypertension and benign prostatic hyperplasia. In summary, yohimbine is the correct answer because it selectively blocks alpha2 receptors, while the other choices are either alpha1-selective or non-selective alpha antagonists.