ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
Concerning argatroban (direct thrombin inhibitor), the following is Wrong:
Correct Answer: C
Rationale: Argatroban is IV, used in HIT, and not reversed by protamine, but it’s monitored by aPTT, not INR (which is for warfarin).
Question 2 of 5
The following is (are) used in acromegaly and in Parkinsonism:
Correct Answer: D
Rationale: Bromocriptine (D2 agonist) treats acromegaly (reduces GH) and Parkinsonism (mimics dopamine). L-dopa also treats Parkinsonism. Octreotide is for acromegaly only.
Question 3 of 5
The following is WRONG concerning leuprolide & nafarelin:
Correct Answer: D
Rationale: Leuprolide and nafarelin (GnRH analogs) stimulate ovulation in pulses for infertility and inhibit gonadotropins continuously for prostate cancer. Continuous use, not pulses, treats endometriosis by suppressing estrogen.
Question 4 of 5
The following is Wrong concerning selective estrogen receptor modulators:
Correct Answer: B
Rationale: Tamoxifen treats breast cancer, not uterine cancer (it increases endometrial cancer risk). Clomiphene induces ovulation, raloxifene treats osteoporosis with thromboembolism risk, and clomiphene causes multiple pregnancies.
Question 5 of 5
The following is true concerning oral contraceptives:
Correct Answer: A
Rationale: Estrogen in oral contraceptives can cause depression. They’re contraindicated in liver disease, minipills have lower thromboembolism risk (not none), cervical mucus thickens (not alkalizes), and medroxyprogesterone lasts ~3 months.