ATI RN
Lymphatic System and Immunity Test Questions Questions
Question 1 of 5
Complete the following sentence. The antibody isotype which displays the highest avidity due to its pentameric form, and is capable of complement recruitment corresponds to.....
Correct Answer: D
Rationale: IgM's pentameric structure gives high avidity and activates complement efficiently.
Question 2 of 5
The major immunoglobulin family to which a particular immunoglobulin belongs can be determined by sequential analysis of the 110 amino acids beginning from the
Correct Answer: C
Rationale: Heavy chain constant region (C-terminus, C) defines isotype; variable regions (A, B) or light chain don't.
Question 3 of 5
Which of the following immune cells/molecules are most effective at destroying intracellular pathogens?
Correct Answer: B
Rationale: T cytolytic cells kill intracellular pathogens; helpers assist, antibodies target extracellular.
Question 4 of 5
Plasma cells are formed by?
Correct Answer: B
Rationale: B lymphocytes differentiate into plasma cells; T cells don't.
Question 5 of 5
Natural killer cells assess whether other cells are abnormal by detecting types and levels of surface-associated
Correct Answer: A
Rationale: MHC class I molecules are self-identification molecules found on all nucleated host cells. Natural killer cells, after making contact with cells expressing stress signals, make the decision whether to kill them or not by assessing whether they express the appropriate types and levels of MHC I molecules. Although they are members of the innate immune system, natural killer cells do not recognize nonself, pathogen-associated molecular patterns, or pattern recognition receptors. Natural killer cells are unable to recognize somatically generated cell surface receptors.