Comparing the arrangement of TCR genes and BCR genes, the chain is analogous to the heavy (H) chain and the chain is analogous to the light (L) chain.

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Ricci Maternity and Pediatrics NCLEX Question Immunization Questions

Question 1 of 5

Comparing the arrangement of TCR genes and BCR genes, the chain is analogous to the heavy (H) chain and the chain is analogous to the light (L) chain.

Correct Answer: B

Rationale: In TCRs, the beta (β) chain is analogous to the heavy chain, and the alpha (α) chain is analogous to the light chain.

Question 2 of 5

CD4 and CD8 enhance the response of specific T cells, both by stabilizing the TCR-peptide-MHC complex and by bringing what type of protein kinase into the proximity of the cytoplasmic tails, thereby facilitating signal transduction and cell activation?

Correct Answer: D

Rationale: Tyrosine kinases (e.g., Lck) are brought into proximity by CD4 and CD8 for signal transduction.

Question 3 of 5

Which of the following is NOT a structural chain in class II MHC?

Correct Answer: C

Rationale: Class II MHC includes α1, α2, β1, and β2, but not α3.

Question 4 of 5

Dual recognition: self MHC + peptide antigen

Correct Answer: B

Rationale: TCRαβ recognizes self MHC plus peptide antigen.

Question 5 of 5

In the processing pathway for intracellular antigens, the proteasome will viral protein molecules until peptides of residues are formed; these can bind to class I MHC molecules.

Correct Answer: C

Rationale: The proteasome breaks down intracellular (e.g., viral) proteins into peptides of 8-11 residues, suitable for MHC Class I binding.

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