ATI RN
ATI Pharmacology Assessment 2 Questions
Question 1 of 5
Colchicine is prescribed for a client with gout. The nurse reviews the client’s record, knowing that this medication would be used in caution in which of the following medical conditions?
Correct Answer: B
Rationale: Colchicine should be used with caution in patients with aplastic anemia or other blood dyscrasias, as it can exacerbate bone marrow suppression. While colchicine is used to treat conditions like Behcet disease and familial Mediterranean fever, it is not contraindicated in these conditions. Amyloidosis is not a primary concern with colchicine use. Monitoring blood counts is essential in patients with pre-existing hematologic conditions.
Question 2 of 5
The patient with schizophrenia is sitting quietly in a chair. The patient does not respond much to what is happening and has a lack of interest in the environment. How does the nurse interpret this assessment?
Correct Answer: D
Rationale: Schizophrenia's negative symptoms include apathy and withdrawal, seen in quietness and disinterest . Depression needs more evidence. Voices suggest positive symptoms, absent here. Positive symptoms add behaviors, not subtract. D aligns with schizophrenia's clinical presentation, making it the correct interpretation.
Question 3 of 5
The patient has been depressed, and the physician plans to begin treatment with an antidepressant medication. In performing the initial assessment, what is the most important question for the nurse to ask?
Correct Answer: D
Rationale: Suicide risk is critical in depression-antidepressants may increase it early (e.g., energy before mood lifts), per black box warnings. Alcohol use, allergies, and duration matter but aren't immediate life threats. Suicidal thoughts guide urgent intervention, per psychiatric priority.
Question 4 of 5
The following drugs are most commonly associated with nephrotoxicity:
Correct Answer: A
Rationale: Gentamicin is associated with nephrotoxicity, particularly when administered in high doses or for prolonged periods.
Question 5 of 5
Which of the following refers to the metabolism of the drug en route from the GUT lumen to the systemic circulation.
Correct Answer: B
Rationale: The first pass effect refers to the metabolism of a drug occurring as it passes from the gastrointestinal tract (GUT lumen) to the liver, before reaching the systemic circulation. This process can significantly reduce the amount of active drug that enters systemic circulation, impacting the drug's overall effectiveness. The first pass effect is an important consideration in pharmacokinetics as it affects the bioavailability of a drug and influences dosing regimens. Options A, C, D, and E do not specifically pertain to the metabolism of a drug en route from the GUT lumen to the systemic circulation as described in the question.