Clomiphene acts to induce ovulation by which of the following mechanisms?

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Pharmacology CNS Drugs Quizlet Questions

Question 1 of 5

Clomiphene acts to induce ovulation by which of the following mechanisms?

Correct Answer: A

Rationale: Clomiphene (choice A), a selective estrogen receptor modulator (SERM), induces ovulation by blocking estrogen receptors in the hypothalamus and pituitary, diminishing negative feedback. This increases gonadotropin (FSH/LH) release, stimulating ovarian follicle development, crucial for infertility treatment. Increasing ERa action (choice B) or amount (choice C) would suppress gonadotropins, countering its purpose. Decreasing gonadotropin secretion (choice D) is the opposite effect, as clomiphene boosts it. By disrupting estrogen's inhibitory signal, clomiphene mimics a low-estrogen state, prompting the pituitary to enhance ovulation. This mechanism distinguishes it from other fertility drugs, highlighting its role in anovulatory conditions like polycystic ovary syndrome, where precise hormonal manipulation is key to success.

Question 2 of 5

Vasodilation by prostaglandins involves

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Following is an example of a preformed, not lipid-derived, mast cell mediator of inflammation

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

The enzyme responsible for producing inflammatory prostaglandins is

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

FDA-approved ingredient for sensitive teeth protection is

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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