ATI RN
Pharmacology of Drugs Acting on Cardiovascular System Slideshare Questions
Question 1 of 5
Class of OKT-3 is:
Correct Answer: B
Rationale: The class of OKT-3 is monoclonal antibodies. OKT-3 is a specific monoclonal antibody used for immunosuppression in organ transplant recipients. Monoclonal antibodies are designed to target specific antigens or proteins in the body. Other choices are incorrect as interferons are cytokines, immunoglobulins are antibodies produced by plasma cells, and immunosuppressive agents are a broad category that includes various drugs targeting the immune system.
Question 2 of 5
Gemfibrozil (Lopid) increases concentrations of HDL cholesterol more than clofibrate (Atromid-S). This consideration is:
Correct Answer: A
Rationale: The correct answer is A: TRUE. Gemfibrozil (Lopid) is known to be more effective at increasing HDL cholesterol levels compared to clofibrate (Atromid-S). This is supported by clinical studies showing a greater impact on HDL concentrations with gemfibrozil. Choice B is incorrect as it contradicts the established evidence. Choices C and D are also incorrect as they do not accurately reflect the comparative efficacy between Gemfibrozil and clofibrate in increasing HDL cholesterol levels.
Question 3 of 5
Commercially available analogs of 1,25-dihydroxyvitamin D3 (calcitriol) are:
Correct Answer: C
Rationale: Rationale: 1. Both Doxercalciferol (Hectoral) and Paricalcitol (Zemplar) are synthetic analogs of 1,25-dihydroxyvitamin D3. 2. Doxercalciferol is converted to calcitriol in the body. 3. Paricalcitol is a selective vitamin D receptor activator. Summary: A: Doxercalciferol is correct as it is a synthetic analog of calcitriol. B: Paricalcitol is correct as it is also a synthetic analog of calcitriol. C: Correct as both A and B are true. D: Incorrect as both A and B are commercially available analogs of calcitriol.
Question 4 of 5
The drug is a potassium-sparing diuretic that blocks Na+ channels in the collecting tubules:
Correct Answer: B
Rationale: The correct answer is B: Amiloride (Midamor). It is a potassium-sparing diuretic that blocks Na+ channels in the collecting tubules. Amiloride specifically targets the epithelial sodium channels in the collecting tubules, leading to decreased sodium reabsorption and potassium retention. Acetazolamide (A) is a carbonic anhydrase inhibitor, Furosemide (C) is a loop diuretic that inhibits the Na+-K+-2Cl- symporter, and Hydrochlorothiazide (D) is a thiazide diuretic that inhibits the Na+-Cl- symporter in the distal convoluted tubule.
Question 5 of 5
Tick the drug belongs to antibiotics-cephalosporins:
Correct Answer: B
Rationale: The correct answer is B: Cefaclor. Cefaclor belongs to the cephalosporin class of antibiotics, specifically a second-generation cephalosporin. Cephalosporins are beta-lactam antibiotics that inhibit bacterial cell wall synthesis. Streptomycin (A) is an aminoglycoside antibiotic, Phenoxymethylpenicillin (C) is a penicillin antibiotic, and Erythromycin (D) is a macrolide antibiotic. These choices do not belong to the cephalosporin class.