ATI RN
Drugs Affecting the Female Reproductive System NCLEX Quizlet Questions
Question 1 of 5
Circulating testosterone levels in men are elevated during treatment with:
Correct Answer: A
Rationale: The correct answer is A: Danazol. Danazol is a synthetic androgen that suppresses gonadotropin secretion, leading to elevated testosterone levels. Finasteride inhibits 5-alpha-reductase, reducing dihydrotestosterone levels. Flutamide is an androgen receptor antagonist, lowering testosterone levels. Ketoconazole inhibits steroid synthesis, decreasing testosterone production. Therefore, only Danazol directly increases circulating testosterone levels in men.
Question 2 of 5
Estrogen therapy can worsen the following associated conditions except:
Correct Answer: B
Rationale: Estrogen therapy can worsen conditions that are sensitive to hormonal fluctuations. Cholelithiasis (gallstones) is not influenced by estrogen levels, so it is not worsened by estrogen therapy. Migraine, acne vulgaris, and endometriosis are conditions known to be affected by estrogen levels and can potentially worsen with estrogen therapy. Therefore, the correct answer is B. Migraine can worsen due to estrogen's impact on blood vessels, acne vulgaris can worsen due to increased sebum production, and endometriosis can worsen due to estrogen's role in promoting tissue growth.
Question 3 of 5
Select the compound which used for hormone replacement therapy in postmenopausal women serves the purpose of both estrogen and progestin with weak androgenic activity:
Correct Answer: A
Rationale: Rationale: 1. Tibolone is a compound used for hormone replacement therapy in postmenopausal women. 2. Tibolone serves the purpose of both estrogen and progestin. 3. It has weak androgenic activity, making it suitable for menopausal symptoms. 4. Mestranol is an estrogen-only compound, not suitable for progestin effects. 5. Desogestrel and Gestodene are progestins but do not have estrogenic properties. In summary, Tibolone is the correct choice as it combines estrogen and progestin with weak androgenic activity, unlike the other options.
Question 4 of 5
The following drug can cause rickets in children by interfering with vitamin D action:
Correct Answer: A
Rationale: The correct answer is A: Tetracycline. Tetracycline can cause rickets in children by binding to calcium in bones, inhibiting bone growth. This interference with vitamin D action leads to impaired calcium absorption. Digoxin, Phenytoin, and Ciprofloxacin do not interfere with vitamin D metabolism or calcium absorption, ruling them out as potential causes of rickets in children.
Question 5 of 5
Parathormone receptors are expressed on the surface of:
Correct Answer: D
Rationale: The correct answer is D because parathormone receptors are expressed on the surface of osteoblasts, osteoclasts, and gut mucosal cells. Parathormone regulates calcium and phosphate levels in the body, influencing bone metabolism and intestinal absorption. Osteoblasts are bone-forming cells, osteoclasts are bone-resorbing cells, and gut mucosal cells are involved in calcium absorption. Therefore, parathormone receptors are present on all three cell types to coordinate calcium homeostasis. Choices A, B, and C are incorrect because parathormone receptors are not exclusive to any one cell type but are present on all three mentioned in the question.