ATI RN
Pediatric Genetic Questions
Question 1 of 5
Chronic myeloid leukemia is caused by a translocation that creates:
Correct Answer: D
Rationale: The BCR-ABL fusion protein from t(9;22) is a tyrosine kinase that deregulates myeloid cell proliferation.
Question 2 of 5
Which of these are thought to have anti-cancer benefits?
Correct Answer: B
Rationale: Cruciferous vegetables (e.g., broccoli) contain compounds (e.g., sulforaphane) linked to reduced cancer risk.
Question 3 of 5
Most carcinogens are also mutagens:
Correct Answer: A
Rationale: True. Most carcinogens (e.g., UV, tobacco smoke) cause cancer by inducing DNA mutations.
Question 4 of 5
Normal human eggs have:
Correct Answer: A
Rationale: Human eggs (haploid) have 23 chromosomes: 22 autosomes + 1 sex chromosome (X).
Question 5 of 5
Male breast cancer is associated with mutations in:
Correct Answer: B
Rationale: BRCA2 mutations increase male breast cancer risk more than BRCA1.