Chris is a 20-year-old college student who has had abdominal pain for 3 days. It started at his umbilicus and was associated with nausea and vomiting. He was unable to find a comfortable position. Yesterday, the pain became more severe and constant. Now, he hesitates to walk, because any motion makes the pain much worse. It is localized just medial and inferior to his iliac crest on the right. Which of the following is most likely?

Correct Answer: D

Rationale: The presentation is highly suggestive of appendicitis, especially given the migration of pain from the periumbilical region to the right lower quadrant (just medial and inferior to the iliac crest). The worsening of pain with motion, along with associated symptoms such as nausea, vomiting, anorexia, and fever, are typical features of appendicitis. The classic presentation of appendicitis is pain starting around the umbilicus (due to visceral innervation) and then shifting to the right lower quadrant (due to irritation of the parietal peritoneum). Surgical intervention is usually required promptly to prevent complications like perforation, which can lead to peritonitis and sepsis.

Correct Answer: A

Rationale: In order to listen carefully for S splitting, one should use the diaphragm with light pressure over the 2nd right intercostal space. S splitting refers to a split of the second heart sound (S2) into its two components - A2 and P2. The A2 component is normally heard as the main heart sound when the aortic valve closes, and the P2 component is heard when the pulmonic valve closes. By placing the diaphragm lightly over the 2nd right intercostal space, one can best auscultate the aortic area and listen for the timing and splitting of the S2 components. Using the bell or applying firm pressure may not allow for optimal detection of S splitting in this specific case.

Correct Answer: C

Rationale: The symptoms described, such as sneezing, itchy watery eyes, clear nasal discharge, ear pain, and nonproductive cough, are classic signs of allergic rhinitis, commonly known as seasonal allergies. Allergic rhinitis is an inflammatory response triggered by allergens in the environment such as pollen, dust mites, or pet dander. The immune system overreacts to these allergens, releasing histamine and other chemicals that cause the symptoms experienced by the patient. In this case, the most likely pathologic process underlying the symptoms is an allergic response rather than infection, inflammation, or vascular issues.

Correct Answer: D

Rationale: HPV (human papillomavirus) infection is a very common sexually transmitted infection (STI) that can affect both men and women. It is the most common STI in the United States. While most cases of HPV infection are asymptomatic and resolve on their own, certain high-risk strains of HPV can lead to the development of various cancers, including cervical cancer. Therefore, HPV infections do cause a small but important number of cervical cancers, making option D the correct choice. Regular screening, such as Pap smears and HPV testing, are crucial for early detection and effective management of HPV-related abnormalities that could progress to cervical cancer.

Correct Answer: D

Rationale: A rectal polyp is a growth that originates from the inner lining of the rectum and protrudes into the rectal canal. It may present as a soft, smooth, nontender mass on digital rectal examination. Rectal polyps are usually benign, but some may have the potential to become cancerous if left untreated. Therefore, it is important to evaluate and remove polyps to prevent complications. In this case, the description of a pedunculated mass on the posterior wall of the rectum is most suggestive of a rectal polyp.

Correct Answer: C

Rationale: Constrictive pericarditis is a condition where the pericardium becomes thickened and rigid, impairing diastolic filling of the heart. This leads to an increase in venous pressure, including the jugular venous pressure (JVP). The elevated JVP in constrictive pericarditis is a result of impaired ventricular filling rather than forward failure seen in heart failure. Mitral stenosis can lead to an increased JVP due to elevated left atrial pressure, but constrictive pericarditis is a more common cause of elevated JVP in this scenario. Aortic aneurysm is not typically associated with elevated JVP.

Correct Answer: B

Rationale: The dullness in the last intercostal space in the anterior axillary line on the left side with a deep breath is suggestive of splenomegaly. However, this finding alone is not definitive for an enlarged spleen. The size of the spleen can vary, and further examination is required to confirm if the spleen is indeed enlarged. Therefore, Option B is the most appropriate choice as it indicates that the spleen is possibly enlarged, and close attention should be paid to further examination to confirm its status. Further workup, such as imaging studies or blood tests, may be necessary to evaluate the size and function of the spleen in this case.

Correct Answer: D

Rationale: Audiometric testing is a very sensitive method for detecting hearing loss. It involves a series of tests that measure a person's ability to hear sounds at various frequencies and volumes. These tests can detect even subtle changes in hearing ability and provide detailed information on the type and degree of hearing loss. The whisper test and finger rub test are basic screening tests and are not as sensitive or comprehensive as audiometric testing. The tuning fork test is also used in evaluating hearing loss, but it is not as accurate or sensitive as audiometric testing. Overall, audiometric testing is considered the gold standard for diagnosing hearing loss due to its high sensitivity and ability to provide detailed information on the individual's hearing capabilities.

Correct Answer: A

Rationale: When crackles, wheezes, or rhonchi clear with a cough, it is suggestive of bronchitis. Bronchitis is inflammation of the bronchial tubes, often due to a viral infection, leading to the production of excess mucus. The characteristic sounds such as crackles, wheezes, or rhonchi can be heard on auscultation due to the presence of mucus in the airways. The act of coughing helps to clear the mucus from the airways, resulting in the temporary resolution of these abnormal sounds. In contrast, asthma, cystic fibrosis, and heart failure are not typically associated with crackles, wheezes, or rhonchi that clear with a cough.