Choose the group of antihypertensive drugs which diminishes the metabolism of bradykinin:

Correct Answer: C

Rationale: The correct answer is C: Angiotensin-converting enzyme inhibitors. These drugs inhibit the enzyme that breaks down bradykinin, leading to its accumulation. Ganglioblockers (A) and Alfa-adrenoblockers (B) do not directly affect bradykinin metabolism. Diuretics (D) primarily act on sodium and water balance, not bradykinin metabolism. In summary, C is correct as ACE inhibitors specifically inhibit bradykinin breakdown, while the other choices do not target this mechanism.

Correct Answer: D

Rationale: Step 1: Estrogens are required for normal sexual maturation and growth of the female. This is true as estrogens play a key role in the development of secondary sexual characteristics and growth. Step 2: Estrogens decrease the rate of resorption of bone. This is true as estrogens help maintain bone density by inhibiting bone breakdown. Step 3: Estrogens enhance the coagulability of blood. This is true as estrogens can increase clotting factors leading to enhanced blood coagulability. Step 4: Combining the above points, it is evident that all the statements are true, making choice D the correct answer. Other choices are incorrect as they do not align with the established functions of estrogens.

Correct Answer: D

Rationale: The correct answer is D because aspirin can cause gastric upset, salicylism symptoms like vomiting, tinnitus, decreased hearing, and vertigo, as well as gastric ulcers and upper gastrointestinal bleeding. Aspirin is known to irritate the stomach lining, leading to gastric upset and ulcers. Salicylism symptoms are characteristic of aspirin toxicity. Gastrointestinal bleeding is a serious side effect of aspirin due to its effect on blood clotting. Choices A, B, and C individually describe common side effects of aspirin, but only choice D encompasses all the side effects associated with aspirin use.

Correct Answer: B

Rationale: The class of OKT-3 is monoclonal antibodies. OKT-3 is a specific monoclonal antibody used for immunosuppression in organ transplant recipients. Monoclonal antibodies are designed to target specific antigens or proteins in the body. Other choices are incorrect as interferons are cytokines, immunoglobulins are antibodies produced by plasma cells, and immunosuppressive agents are a broad category that includes various drugs targeting the immune system.

Correct Answer: C

Rationale: Step-by-step rationale: 1. Polar bear liver contains high levels of Vitamin A. 2. Excessive Vitamin A intake can lead to acute poisoning. 3. Symptoms of Vitamin A poisoning include nausea, vomiting, dizziness, and even death. 4. Thus, ingestion of polar bear liver can cause acute poisoning due to Vitamin A overload. Summary: A: Vitamin D - Incorrect. Polar bear liver does not contain toxic levels of Vitamin D. B: Vitamin E - Incorrect. Vitamin E toxicity is rare and not associated with polar bear liver ingestion. C: Vitamin A - Correct. Polar bear liver is high in Vitamin A, leading to acute poisoning if consumed in excess. D: Vitamin C - Incorrect. Vitamin C toxicity is unlikely from consuming polar bear liver.