Childhood vasculitis encompasses a broad spectrum of diseases that share inflammation of blood vessels. The disease that affects predominantly large blood vessels is

Correct Answer: D

Rationale: Takayasu arteritis primarily affects large arteries.

Correct Answer: D

Rationale: The major objective of therapy in cystic fibrosis (CF) is to promote the removal of secretions from the lungs. Chest physiotherapy, which involves postural drainage, vibration, and percussion, has been the mainstay of treatment for CF patients. This technique helps loosen and clear mucus from the airways, reducing the risk of lung infections and improving respiratory function. Aerobic exercise is also effective in clearing the airways and is an essential part of the treatment plan for CF patients. While prophylactic antibiotics may be used for early signs of infection, they are not the most effective treatment for CF. Nebulized bronchodilators do not provide long-term benefits for CF patients. Heart-lung transplant may be considered for some CF patients, but it is not a suitable option for most individuals due to various limitations and availability issues. Therefore, the most effective treatment for cystic fibrosis is

Correct Answer: C

Rationale: Feeling very sad or withdrawn for more than 2 months is part of the Mental Health Action Signs, but the phrase 'for more than 2 months' is not accurate as symptoms lasting 2 weeks can already be significant.

Correct Answer: D

Rationale: Uninvolved skin in atopic dermatitis patients often has over 50% colonization with S. aureus.

Correct Answer: D

Rationale: HIV is not typically transmitted transplacentally in significant amounts due to antiretroviral therapy. Cytomegalovirus, herpes simplex virus, and varicella-zoster virus are known to cause meningoencephalitis in affected infants.