ATI RN
NCLEX questions on chemotherapy drugs Questions
Question 1 of 5
Chemical interactions between this drug and cell membrane components can result in the formation of pores lined by hydrophilic groups present in the drug molecule.
Correct Answer: D
Rationale: Nystatin, a polyene antifungal, binds to ergosterol in fungal cell membranes, forming pores that disrupt membrane integrity and cause cell death.
Question 2 of 5
Which of the following drugs is most likely to cause additive anemia and neutropenia if administered to an AIDS patient taking zidovudine?
Correct Answer: C
Rationale: Ganciclovir causes bone marrow suppression, including anemia and neutropenia, which can be additive with zidovudine’s similar effects.
Question 3 of 5
Over 90% of this drug is excreted in the urine in intact form. Because its urinary solubility is low, patients should be well hydrated to prevent nephrotoxicity
Correct Answer: A
Rationale: Acyclovir is excreted mostly unchanged in urine and can crystallize in the kidneys, necessitating hydration to prevent nephrotoxicity.
Question 4 of 5
Infections due to gram-negative bacilli have occurred when this agent has been used as a skin antiseptic
Correct Answer: B
Rationale: Benzalkonium chloride, a quaternary ammonium compound, has been associated with gram-negative infections due to contamination.
Question 5 of 5
Which one of the following antiseptics promotes wound healing?
Correct Answer: D
Rationale: None of these antiseptics are proven to promote wound healing; they primarily prevent infection rather than enhance tissue repair.