Characteristics of beta-blocking agents include all of the following EXCEPT:

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Clinical Pharmacology of Cardiovascular Drugs PPT Questions

Question 1 of 5

Characteristics of beta-blocking agents include all of the following EXCEPT:

Correct Answer: C

Rationale: The correct answer is C because beta-blocking agents do not induce depression or deplete stores of catecholamines. Here's the rationale: 1. Option A is correct as beta blockers occupy beta receptors, competitively reducing receptor occupancy by catecholamines. 2. Option B is incorrect because beta blockers can cause hypotension as one of their side effects, especially in individuals with normal blood pressure. 3. Option D is correct as beta blockers can cause blockade in the atrioventricular node, leading to decreased heart rate and conduction. In summary, beta blockers do not induce depression or deplete catecholamine stores, making option C the correct answer.

Question 2 of 5

Indicate the antiseizure drug – a benzodiazepine receptor agonist:

Correct Answer: D

Rationale: The correct answer is D: Lorazepam. Lorazepam is a benzodiazepine receptor agonist, which enhances the inhibitory effect of GABA in the brain, reducing neuronal excitability and preventing seizures. Phenobarbital (A) acts by enhancing GABAergic transmission but is not a benzodiazepine. Phenytoin (B) works by blocking sodium channels. Carbamazepine (C) also blocks sodium channels but is not a benzodiazepine receptor agonist. Therefore, D is the correct answer as it directly acts on the benzodiazepine receptor to control seizures.

Question 3 of 5

Select the brain and spinal cord regions which are involved in the transmission of pain?

Correct Answer: D

Rationale: The correct answer is D because all of the mentioned regions are involved in the transmission of pain. The limbic system processes emotions related to pain. The thalamus relays sensory information to the cortex. The substantia gelatinosa in the spinal cord regulates pain signals. Each region plays a crucial role in the pain pathway, from perception to emotional response. Choices A, B, and C are incorrect because each region mentioned is directly involved in pain transmission.

Question 4 of 5

Indicate the “specific” modality of treatment for severe methanol poisoning:

Correct Answer: D

Rationale: The correct answer is D because severe methanol poisoning requires a multi-modal approach. Dialysis enhances methanol removal. Alkalinization helps counteract metabolic acidosis. Suppressing metabolism by alcohol dehydrogenase prevents the formation of toxic products. Therefore, all options (A, B, and C) are necessary for effective treatment of severe methanol poisoning. Other choices are incorrect as they do not address the multiple facets of methanol toxicity.

Question 5 of 5

The mechanism of haloperidol antipsychotic action is:

Correct Answer: A

Rationale: The correct answer is A: Blocking D2 receptors. Haloperidol is a typical antipsychotic that primarily works by blocking dopamine D2 receptors in the brain, leading to a reduction in dopamine activity and alleviating psychotic symptoms. Choices B and C are incorrect as haloperidol does not primarily act by central alpha-adrenergic blocking or inhibition of norepinephrine uptake mechanisms. Choice D, "All of the above," is incorrect as haloperidol's main mechanism of action is through D2 receptor blockade, not through all the mechanisms listed.

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