Cellular interactions between B and T cells involve costimulatory activation. There is a physical interaction between ___ on the B cell and ___ on the T cell. This leads to a B cell producing high affinity antibody.

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

Cellular interactions between B and T cells involve costimulatory activation. There is a physical interaction between ___ on the B cell and ___ on the T cell. This leads to a B cell producing high affinity antibody.

Correct Answer: C

Rationale: CD40 (B cell) and CD154 (T cell) interaction is critical for B-cell activation and antibody affinity maturation.

Question 2 of 5

Mucociliary escalator

Correct Answer: B

Rationale: The mucociliary escalator in the upper respiratory tract clears pathogens.

Question 3 of 5

Which complement pathway is activated by (and requires) antibodies, with IgM being particularly good at C1 binding?

Correct Answer: B

Rationale: The classical pathway requires antibodies, with IgM effectively binding C1.

Question 4 of 5

Follows concentration gradient of chemokines to the site of infection

Correct Answer: B

Rationale: Chemotaxis is the movement along chemokine gradients.

Question 5 of 5

Most cases of septic shock are caused by gram organisms with the acting as the endotoxin in the disease.

Correct Answer: B

Rationale: Gram-negative bacteria are the most common cause of septic shock, and their lipopolysaccharide (LPS) endotoxin triggers the inflammatory response.

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