ATI RN
Lymphatic and Immune System Test Questions Questions
Question 1 of 5
CD8+ T cell activation requires CD4+ T cell help because
Correct Answer: A
Rationale: CD4+ help (via cytokines like IL-2) regulates CD8+ activation, preventing excessive cytotoxicity.
Question 2 of 5
B cells mature in the_____________.. while T cells mature in the
Correct Answer: C
Rationale: B cells mature in bone marrow/GALT, T cells in thymus ; not thymus first or spleen/liver (B, D).
Question 3 of 5
B lymphocytes is related to:
Correct Answer: A
Rationale: B cells relate to Bursa Fabricius in birds, bone marrow in humans; not thymus .
Question 4 of 5
Immune recognition of molecules belonging to self is important to
Correct Answer: B
Rationale: Identification of self tells the immune system that the cell or molecule recognized is not a foe. Natural killer cells use this mechanism of self-recognition to halt their attack on cells that they perceive to be abnormal. Receptor generation by B and T cells occurs independently of initial encounter with self molecules. Pattern recognition receptors, on the other hand, are genetically programmed to recognize nonself. By triggering an attack on a cell expressing the self molecule, an immune recognition molecule violates its 'nonaggression pact' with the cells and molecules of the host and establishes an internal coup known as autoimmunity.
Question 5 of 5
The Fc region mediates all of the below EXCEPT binding to
Correct Answer: A
Rationale: The Fc region binds immune cells and lysosomes for effector functions, but antigen binding occurs at the variable region.