ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
CD4 molecules bind with MHC molecules and are found on (expressed by) cells. CD8 molecules bind with MHC molecules and are found on (expressed by) cells.
Correct Answer: C
Rationale: CD4 binds MHC class II on helper T cells; CD8 binds MHC class I on cytotoxic T cells.
Question 2 of 5
Rhematoid arthritis
Correct Answer: D
Rationale: Rheumatoid arthritis is associated with HLA-DR4.
Question 3 of 5
In the processing pathway for extracellular antigens, synthesis of MHC class II and invariant chain (li) occurs in the
Correct Answer: C
Rationale: MHC Class II and invariant chain synthesis occurs in the endoplasmic reticulum, where they are assembled before trafficking to vesicles.
Question 4 of 5
Regarding the structure of the T-cell receptor, which of the following is NOT an invariant CD3 protein chain?
Correct Answer: A
Rationale: The TCR includes CD3 chains (γ, δ, ε) and theζ chain, butζ is not traditionally classified as a CD3 chain; it's part of the associatedζ-ζ homodimer.
Question 5 of 5
Which of the following are lineage restricted, morphologically identifiable, and express differentiation markers?
Correct Answer: C
Rationale: Mature cells are fully differentiated, lineage-restricted, and express specific markers.