ATI RN
Ricci Maternity and Pediatrics NCLEX Question Immunization Questions
Question 1 of 5
CD4 and CD8 enhance the response of specific T cells, both by stabilizing the TCR-peptide-MHC complex and by bringing what type of protein kinase into the proximity of the cytoplasmic tails, thereby facilitating signal transduction and cell activation?
Correct Answer: D
Rationale: Tyrosine kinases (e.g., Lck) are brought into proximity by CD4 and CD8 for signal transduction.
Question 2 of 5
Dual recognition: self MHC + peptide antigen
Correct Answer: B
Rationale: TCRαβ recognizes self MHC plus peptide antigen.
Question 3 of 5
In the processing pathway for intracellular antigens, the proteasome will viral protein molecules until peptides of residues are formed; these can bind to class I MHC molecules.
Correct Answer: C
Rationale: The proteasome breaks down intracellular (e.g., viral) proteins into peptides of 8-11 residues, suitable for MHC Class I binding.
Question 4 of 5
The B cell co-receptor can co-cluster with the BCR and increase the efficiency of signaling. Which of the following proteins does NOT make up the co-receptor?
Correct Answer: B
Rationale: The B cell co-receptor includes CD19, CD21, and CD81; CD20 is a separate B cell marker not part of the co-receptor.
Question 5 of 5
Lyse certain virally infected cells and some tumor cells
Correct Answer: D
Rationale: T-cytotoxic (CD8+) cells lyse virally infected and tumor cells.