ATI RN
Drugs Affecting the Female Reproductive System Quizlet Exam Questions
Question 1 of 5
Carbimazole acts by inhibiting:
Correct Answer: B
Rationale: Carbimazole inhibits the oxidation of iodide by blocking the enzyme thyroid peroxidase. This enzyme is crucial for converting iodide to iodine, a key step in thyroid hormone synthesis. By inhibiting this step, carbimazole effectively reduces the production of thyroid hormones. Choice A is incorrect as iodide trapping is not directly affected by carbimazole. Choice C is incorrect as proteolysis of thyroglobulin is not the target of carbimazole. Choice D is incorrect as carbimazole does not interfere with the synthesis of thyroglobulin protein itself.
Question 2 of 5
Insulin release from pancreatic β cells is augmented by the following except:
Correct Answer: A
Rationale: Insulin release is primarily stimulated by glucose. Ketone bodies are produced during fasting or low-carb diets and do not directly stimulate insulin release. Glucagon stimulates glycogen breakdown and opposes insulin. Vagal stimulation can enhance insulin release through parasympathetic nervous system activation. Alpha adrenergic agonists like epinephrine inhibit insulin release. Therefore, the correct answer is A as ketone bodies do not directly augment insulin release.
Question 3 of 5
The primary route of administration of insulin is:
Correct Answer: B
Rationale: The correct answer is B: Subcutaneous. Insulin is typically administered subcutaneously because it allows for slow and consistent absorption into the bloodstream. Intradermal administration is not ideal for insulin as it may cause skin irritation. Intramuscular administration can lead to erratic absorption and unpredictable blood sugar levels. Intravenous administration is too rapid and can cause dangerous hypoglycemia. Subcutaneous administration provides a balance of absorption rate and is the most common and effective route for insulin delivery.
Question 4 of 5
In a patient of diabetes mellitus maintained on insulin therapy, administration of the following drug can impair glycaemia control:
Correct Answer: A
Rationale: Step-by-step rationale for why choice A (Prednisolone) is correct: 1. Prednisolone is a corticosteroid that can cause hyperglycemia by increasing insulin resistance. 2. This drug can lead to elevated blood glucose levels and worsen glycemic control in diabetic patients. 3. Prednisolone can counteract the effects of insulin, making it difficult to maintain stable blood sugar levels. 4. Therefore, in a patient with diabetes mellitus on insulin therapy, the addition of prednisolone can impair glycemic control. Summary of why the other choices are incorrect: B: Prazosin is an alpha-blocker used to treat hypertension, it does not directly affect glycemia control. C: Paracetamol is an analgesic with no direct impact on blood glucose levels. D: Phenytoin is an antiepileptic drug that does not interfere with glycemic control in diabetes mellitus patients on insulin therapy.
Question 5 of 5
Compared to pork/beef insulins, the human insulins:
Correct Answer: B
Rationale: The correct answer is B: Human insulins have a faster kinetics of absorption and elimination compared to pork/beef insulins. This is because human insulins are structurally identical to the insulin produced by the human body, leading to better compatibility and quicker absorption. Pork/beef insulins may have different amino acid sequences, causing slower absorption. Choice A is incorrect as potency is not the distinguishing factor between human and pork/beef insulins. Choice C is incorrect because human insulins typically have shorter biological action half-lives due to faster absorption. Choice D is irrelevant as it does not relate to the comparison between human and pork/beef insulins.