Broadspectrum antibiotics can cause various complications, including intestinal candidiasis. What drug is used for treatment of this complication?

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Microbiology An Evolving Science Test Bank Questions

Question 1 of 9

Broadspectrum antibiotics can cause various complications, including intestinal candidiasis. What drug is used for treatment of this complication?

Correct Answer: A

Rationale: The correct answer is A: Nystatin. Nystatin is specifically used to treat intestinal candidiasis because it targets and eliminates the Candida species responsible for the infection. It is not absorbed systemically, acting only locally in the gastrointestinal tract. Griseofulvin (B) is mainly used to treat fungal skin infections, not intestinal candidiasis. Undecyne (C) is an antifungal agent used for skin infections, not for intestinal candidiasis. Amphotericin B (D) is a potent antifungal agent used for systemic fungal infections, not specifically for intestinal candidiasis.

Question 2 of 9

Which of the following statements for genus Klebsiella is correct?

Correct Answer: A

Rationale: The correct answer is A because Klebsiella species have a real capsule, which is a distinguishing feature used for their identification. This capsule helps them evade the host immune response. Additionally, Klebsiella species are non-motile, meaning they do not possess flagella for movement. Choices B and C are incorrect because Klebsiella species are facultative anaerobes and do not form spores under any conditions. Choice D is also incorrect as option A is the correct statement for genus Klebsiella.

Question 3 of 9

Quite often, the soil may contain a number of pathogenic microorganisms. The causative agents of the following disease may exist in the soil for a long time:

Correct Answer: A

Rationale: The correct answer is A: Anthrax. Anthrax is caused by the bacterium Bacillus anthracis, which can form spores that are highly resistant and can survive in the soil for long periods. These spores can remain dormant until they come into contact with a susceptible host, leading to infection. Diphtheria, viral hepatitis, and pertussis are caused by different types of pathogens (bacteria and viruses) that do not have the same ability to persist in soil as anthrax spores. Therefore, the causative agents of these diseases are less likely to exist in the soil for extended periods compared to anthrax spores.

Question 4 of 9

Which bacteria is responsible for causing whooping cough?

Correct Answer: A

Rationale: The correct answer is A: Bordetella pertussis. This bacterium causes whooping cough by attaching to the respiratory tract and releasing toxins that lead to severe coughing fits. Clostridium tetani causes tetanus, not whooping cough. Haemophilus influenzae can cause respiratory infections but not specifically whooping cough. Staphylococcus aureus is known for causing skin infections and not respiratory diseases like whooping cough. Therefore, the presence of Bordetella pertussis and its specific mechanism of causing whooping cough makes it the correct answer.

Question 5 of 9

A 47-year-old male patient consulted a dentist about difficult mouth opening (lockjaw or trismus). The patient has a history of a stab wound of the lower extremity. What infection can be manifested by these symptoms?

Correct Answer: A

Rationale: The correct answer is A: Tetanus. Tetanus is caused by the bacterium Clostridium tetani, commonly found in soil, dust, and animal feces. The patient's history of a stab wound increases the risk of tetanus infection as the bacterium can enter the body through the wound. Tetanus infection can lead to symptoms such as lockjaw or trismus, which are characterized by muscle stiffness and difficulty opening the mouth. This is due to the neurotoxin produced by Clostridium tetani affecting the muscles. Summary of incorrect choices: B: Brucellosis is a bacterial infection transmitted from animals to humans through consumption of unpasteurized dairy products. It does not typically manifest with symptoms of lockjaw. C: Whooping cough (Pertussis) is a respiratory infection caused by Bordetella pertussis bacteria. It presents with severe coughing fits but does not cause lockjaw. D: Anaerobic wound infection

Question 6 of 9

Which of the following media is the most selective for Vibrio cholerae?

Correct Answer: D

Rationale: The correct answer is D: TCBS. Thiosulfate-citrate-bile salts-sucrose (TCBS) agar is the most selective for Vibrio cholerae due to its high salt content, bile salts, and sucrose. Vibrio cholerae can grow well in alkaline conditions, which are provided by TCBS agar. MacConkey's agar (A) is selective for gram-negative bacteria, but not specifically for Vibrio cholerae. Chocolate agar (B) is a non-selective medium suitable for fastidious organisms. SS agar (C) is selective for Salmonella and Shigella species, not Vibrio cholerae.

Question 7 of 9

A patient with probable liver abscess was delivered to a surgical department. The patient for a long time had been on an assignment in an African country and had recurrent cases of gastrointestinal disturbance. What protozoan disease can it be?

Correct Answer: D

Rationale: The correct answer is D: Amebiasis. The patient's symptoms of gastrointestinal disturbance and liver abscess are indicative of an infection with Entamoeba histolytica, the protozoan parasite responsible for amebiasis. The patient's travel history to an African country also increases the likelihood of contracting this disease, as it is more prevalent in tropical regions. Toxoplasmosis (A) is primarily associated with exposure to cat feces, Leishmaniasis (B) is transmitted through sandfly bites, and Malaria (C) is caused by Plasmodium parasites transmitted through mosquito bites. Therefore, these options are incorrect given the patient's presentation and travel history.

Question 8 of 9

A child with fever and a sore throat had a Gram-stained smear revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the likely causative agent?

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. The presence of Gram-positive cocci in chains suggests a streptococcal infection. Beta-hemolysis indicates the production of a hemolysin that lyses red blood cells, a characteristic of Streptococcus pyogenes. This bacterium is known to cause strep throat and can present with fever and sore throat. Summary: - B: Streptococcus pneumoniae is a common cause of pneumonia but typically appears as lancet-shaped cocci, not in chains. - C: Staphylococcus aureus is a gram-positive cocci in clusters, not chains, and is not typically beta-hemolytic. - D: Enterococcus faecalis is a gram-positive cocci that are part of the normal gut flora and are not typically beta-hemolytic or found in chains.

Question 9 of 9

Which of the following is not considered to be a vehicle transmission?

Correct Answer: B

Rationale: The correct answer is B: Insect. A vehicle transmission refers to the mode by which a disease spreads from one host to another. Insects can transmit diseases, making them a vehicle for transmission. Airborne, foodborne, and bodily fluid transmissions are well-known modes of disease spread, while insects are also known vectors for diseases like malaria and Zika.

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