ATI RN
Microbiology An Evolving Science Test Bank Questions
Question 1 of 9
Broadspectrum antibiotics can cause various complications, including intestinal candidiasis. What drug is used for treatment of this complication?
Correct Answer: A
Rationale: The correct answer is A: Nystatin. Nystatin is specifically used to treat intestinal candidiasis because it targets and eliminates the Candida species responsible for the infection. It is not absorbed systemically, acting only locally in the gastrointestinal tract. Griseofulvin (B) is mainly used to treat fungal skin infections, not intestinal candidiasis. Undecyne (C) is an antifungal agent used for skin infections, not for intestinal candidiasis. Amphotericin B (D) is a potent antifungal agent used for systemic fungal infections, not specifically for intestinal candidiasis.
Question 2 of 9
The classic causative agent of croupous pneumonia is:
Correct Answer: B
Rationale: The correct answer is B, Streptococcus pneumoniae. This bacterium is the classic causative agent of croupous pneumonia due to its ability to infect the lungs and cause inflammation. Streptococcus pneumoniae is a common pathogen known for causing pneumonia in both adults and children. It is characterized by the presence of a capsule that helps it evade the host immune system. Choice A, Chlamydia pneumoniae, is not the correct answer as it is more commonly associated with atypical pneumonia. Choice C, Mycoplasma pneumoniae, is also associated with atypical pneumonia and not croupous pneumonia. Choice D, Staphylococcus aureus, can cause pneumonia, but it is not the classic causative agent of croupous pneumonia.
Question 3 of 9
The generic name of a drug refers to its __________ name.
Correct Answer: D
Rationale: The correct answer is D: nonproprietary. The generic name of a drug is the official, nonproprietary name given to a drug by an organization such as the U.S. Food and Drug Administration (FDA). This name is not owned by any specific company and is used universally to identify the drug's active ingredient. The generic name helps to communicate the specific medication being prescribed and allows for cost-effective options for consumers. A: Trade name refers to the brand name given to a drug by a pharmaceutical company. B: Proprietary name is another term for the trade name, specific to the company that produces the drug. C: Chemical name refers to the exact chemical composition of the drug, which may not be user-friendly or easily recognized by healthcare professionals or consumers.
Question 4 of 9
Microscopic analysis of dental plaque revealed flagellated protozoa without a cyst stage. What microorganism is likely present?
Correct Answer: A
Rationale: The correct answer is A: Trichomonas tenax. Trichomonas tenax is a flagellated protozoan commonly found in the oral cavity and does not have a cyst stage. This organism typically inhabits the gingival crevices and can be identified in dental plaque samples. Entamoeba gingivalis (B) is an amoeba and does not have flagella. Balantidium coli (C) is a ciliated protozoan that infects the intestines, not the oral cavity. Giardia lamblia (D) is a flagellated protozoan that infects the intestines and has a distinct cyst stage. Therefore, the presence of flagellated protozoa without a cyst stage in dental plaque indicates Trichomonas tenax is likely present.
Question 5 of 9
What type of immunity is responsible for the agglutination of viruses:
Correct Answer: B
Rationale: The correct answer is B: Humoral immunity. Humoral immunity involves the production of antibodies by B cells that can bind to antigens on viruses, leading to their agglutination. This process prevents the spread of the virus in the body. Passive immunity (A) involves receiving pre-formed antibodies, not the production of antibodies. Cell-mediated immunity (C) involves the activation of T cells, not the direct agglutination of viruses. Non-specific immunity (D) refers to general defense mechanisms like inflammation and fever, not targeted agglutination of viruses.
Question 6 of 9
Protein A is located in the cell wall of:
Correct Answer: B
Rationale: Protein A is a virulence factor specific to Staphylococcus aureus. This protein binds to the Fc region of immunoglobulins, inhibiting opsonization and phagocytosis. Therefore, the correct answer is B. Coagulase negative staphylococcus (choice A) does not produce Protein A. Micrococcus (choice C) is a different genus and does not possess Protein A. Choice D is incorrect because Protein A is indeed found in Staphylococcus aureus.
Question 7 of 9
Which of the following media is the most selective for Vibrio cholerae?
Correct Answer: D
Rationale: The correct answer is D: TCBS. Thiosulfate-citrate-bile salts-sucrose (TCBS) agar is the most selective for Vibrio cholerae due to its high salt content, bile salts, and sucrose. Vibrio cholerae can grow well in alkaline conditions, which are provided by TCBS agar. MacConkey's agar (A) is selective for gram-negative bacteria, but not specifically for Vibrio cholerae. Chocolate agar (B) is a non-selective medium suitable for fastidious organisms. SS agar (C) is selective for Salmonella and Shigella species, not Vibrio cholerae.
Question 8 of 9
Which of the following antibodies is synthesized by the infant soon after birth?
Correct Answer: B
Rationale: The correct answer is B: IgM. IgM is the first antibody synthesized by the infant soon after birth. It is produced by B cells in response to initial exposure to antigens. IgA is mainly found in mucosal areas, IgG is transferred from mother to fetus, and IgD functions in the early stages of B cell development. Therefore, IgM is the most suitable choice as the antibody synthesized by the infant soon after birth.
Question 9 of 9
A child with fever and a sore throat had a Gram-stained smear revealing Gram-positive cocci in chains. The bacteria were beta-hemolytic. What is the likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Streptococcus pyogenes. The presence of Gram-positive cocci in chains suggests a streptococcal infection. Beta-hemolysis indicates the production of a hemolysin that lyses red blood cells, a characteristic of Streptococcus pyogenes. This bacterium is known to cause strep throat and can present with fever and sore throat. Summary: - B: Streptococcus pneumoniae is a common cause of pneumonia but typically appears as lancet-shaped cocci, not in chains. - C: Staphylococcus aureus is a gram-positive cocci in clusters, not chains, and is not typically beta-hemolytic. - D: Enterococcus faecalis is a gram-positive cocci that are part of the normal gut flora and are not typically beta-hemolytic or found in chains.