ATI RN
ASCP Hematology Questions Questions
Question 1 of 5
Blood transfusion therapy in a child with sickle cell anemia is indicated in all the following conditions EXCEPT
Correct Answer: C
Rationale: Transfusions are indicated for acute chest syndrome (A), stroke (B), and splenic sequestration (E) in sickle cell anemia to improve oxygenation or reduce sickle cells. Chronic pain (C) and avascular necrosis (D) are managed symptomatically, not with transfusion.
Question 2 of 5
All the following are correct regarding treatment of cold agglutinin disease EXCEPT
Correct Answer: D
Rationale: Cold agglutinin disease management includes avoiding cold (A), treating underlying causes (B), plasmapheresis (C), and rarely splenectomy (E). Glucocorticoids (D) are ineffective due to intravascular hemolysis.
Question 3 of 5
Transfusion of fresh frozen plasma (FFP) is efficacious for the treatment of deficiency of all the following coagulation factors EXCEPT
Correct Answer: D
Rationale: FFP provides factors V (A), X (B), XI (C), and protein C (E), but factor XIII (D) has low levels in FFP, requiring cryoprecipitate or concentrates for deficiency.
Question 4 of 5
In hemophilia A, factor VIII level activity should be increased to $100 \%$ in
Correct Answer: B
Rationale: Iliopsoas bleeding (B) in hemophilia A is life-threatening, requiring 100% factor VIII correction. Epistaxis (A), extraction (C), hematuria (D), and gum bleeding (E) need lower levels (30-50%).
Question 5 of 5
All the following are true regarding factor XIII EXCEPT
Correct Answer: B
Rationale: Factor XIII has a 5-7 day half-life (A), is screened by clot solubility (C), assayed specifically (D), and needs 2-3% for hemostasis (E). PT, PTT, and TT (B) are normal in its deficiency, as it affects clot stability, not formation.