ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Blockade of which of the following pairs of receptors likely mediated the adverse effect of olanzapine in the 37-year-old woman with a schizoaffective disorder?
Correct Answer: B
Rationale: The most likely receptors mediating the adverse effect of olanzapine in the 37-year-old woman are GABAergic and muscarinic receptors. Olanzapine, an atypical antipsychotic, can have side effects such as acute psychotic states and aggression, which may be due to its interaction with these receptors. Blocking GABAergic receptors can lead to disinhibition and agitation, while muscarinic receptor blockade can cause cognitive impairment and confusion, both of which could contribute to the patient's acute psychotic state and aggressive behavior.
Question 2 of 5
Acute opium poisoning is treated by intravenous administration of
Correct Answer: A
Rationale: Naloxone is an opioid antagonist that rapidly reverses respiratory depression in opioid overdose.
Question 3 of 5
Blockade of which of the following pairs of receptors likely mediated the adverse effect of olanzapine in the 37-year-old woman with a schizoaffective disorder?
Correct Answer: B
Rationale: The most likely receptors mediating the adverse effect of olanzapine in the 37-year-old woman are GABAergic and muscarinic receptors. Olanzapine, an atypical antipsychotic, can have side effects such as acute psychotic states and aggression, which may be due to its interaction with these receptors. Blocking GABAergic receptors can lead to disinhibition and agitation, while muscarinic receptor blockade can cause cognitive impairment and confusion, both of which could contribute to the patient's acute psychotic state and aggressive behavior.
Question 4 of 5
In the treatment of congenital adrenal hyperplasia in which there is excess production of cortisol precursor, the purpose of administration of synthetic glucocorticoid is:
Correct Answer: D
Rationale: In CAH (choice D), synthetic glucocorticoids suppress ACTH, reducing adrenal precursor excess (e.g., 17-hydroxyprogesterone). Aldosterone (choice A), renal (choice B), and immune (choice C) effects aren't primary goals. ACTH suppression corrects the defect.
Question 5 of 5
Which of the following drugs would be useful to treat the patient's condition of repeated head jerking, blinking, and grimacing?
Correct Answer: B
Rationale: Aripiprazole is an antipsychotic medication that is commonly used to treat symptoms of Tourette syndrome, which includes tics like head jerking, blinking, and grimacing. Fluoxetine, clonazepam, naltrexone, and imipramine are not typically used for treating tics associated with Tourette syndrome.