ATI RN
Pharmacology Across the Lifespan Questions
Question 1 of 5
Below question: don't know the correct combination. Below is what was picked but incorrect. An elderly patient with hypertension and hyperlipidemia who has been prescribed a statin medication comes for a follow up visit after four months of therapy. The patient's laboratory reports show elevated blood cholesterol levels, in the urine examination reveals rhabdomyolysis. What would be the reasons for this condition? Select all that apply
Correct Answer: C
Rationale: Rationale: Choice C is correct because consuming fiber-rich foods can interfere with the absorption of statins, leading to decreased effectiveness and potential elevation in cholesterol levels. Fiber binds to statins in the gastrointestinal tract, reducing their absorption. Choices A, B, and D are incorrect because cyclosporine, grapefruit juice, and amiodarone are known to interact with statins but do not directly cause rhabdomyolysis or elevated cholesterol levels in this scenario.
Question 2 of 5
Why should Sumatriptan be used with caution in a patient with angina?
Correct Answer: B
Rationale: The correct answer is B because Sumatriptan, a triptan medication used for migraine treatment, can cause vasoconstriction of blood vessels including the coronary arteries. This vasoconstriction can lead to reduced blood flow to the heart, potentially precipitating an anginal attack in a patient with angina. Choices C and D are incorrect as they also mention vasoconstriction but do not specifically link it to triggering an anginal attack. Choice A is incorrect as it does not provide any relevant information.
Question 3 of 5
Thyroxine has recently been added to the routine medications for a patient who also uses insulin, warfarin, cholestyramine, and antacids daily. Which statement should be included in the patient's medication education?
Correct Answer: C
Rationale: Rationale: - Thyroxine (levothyroxine) is best absorbed on an empty stomach, so it should be taken at least 4 hours apart from medications like cholestyramine, which can interfere with its absorption. - Option A is incorrect because aluminum-containing antacids do not directly interact with levothyroxine. - Option B is incorrect as the dosage of insulin is not typically affected by levothyroxine. - Option D is incorrect as levothyroxine does not directly impact warfarin dosage.
Question 4 of 5
Metformin most likely causes which of the following?
Correct Answer: B
Rationale: The correct answer is B: Increased insulin sensitivity. Metformin works by decreasing hepatic glucose production, increasing peripheral glucose uptake, and improving insulin sensitivity in tissues. It does not increase gluconeogenesis (A), decrease GI glucose absorption (C), or increase pancreatic insulin release (D). By enhancing insulin sensitivity, Metformin helps lower blood glucose levels in individuals with type 2 diabetes.
Question 5 of 5
Which of the following medications is associated with managing gout?
Correct Answer: D
Rationale: The correct answer is D: NSAIDs. NSAIDs are commonly used to manage gout due to their anti-inflammatory properties, which help reduce inflammation and pain associated with gout attacks. They work by inhibiting the enzyme responsible for producing prostaglandins, which are involved in the inflammatory response. Coleseyelam (A) is a cholesterol-lowering medication, not used for gout. Vitamin A (B) is a vitamin and not indicated for gout management. Aminocarproic acid (C) is used to treat excessive bleeding and is not associated with managing gout.