Before a surgery the patient was prescribed a synthetic antiprotozoal drug for prevention of wound infection. The prescribed drug is highly effective against Helicobacter pylori. Name this drug:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is a synthetic antiprotozoal drug commonly used for wound infection prevention. 2. It is highly effective against Helicobacter pylori, a bacterium that causes stomach ulcers. 3. Metronidazole works by disrupting DNA structure in bacteria, leading to their death. 4. Chingamin (Chloroquine) is an antimalarial drug, not effective against Helicobacter pylori. 5. Doxycycline hydrochloride is an antibiotic used for bacterial infections, not specifically for H. pylori. 6. Aciclovir is an antiviral drug used for herpes infections, not effective against H. pylori. Summary: Metronidazole is the correct answer as it is specifically effective against H. pylori and commonly used for wound infection prevention. Other choices are incorrect as they target different types of infections.

Correct Answer: A

Rationale: The correct answer is A: Trichomonas vaginalis. Trichomonas vaginalis is a sexually transmitted protozoan that causes trichomoniasis. The pear-shaped flagellated protozoa with an undulating membrane described in the question match the morphology of Trichomonas vaginalis. It is typically found in vaginal discharge of infected individuals. Giardia lamblia (B) is a different protozoan that causes giardiasis and has a distinct morphology of a teardrop shape with flagella. Trypanosoma brucei (C) causes African sleeping sickness and Leishmania donovani (D) causes visceral leishmaniasis, both of which have different morphologies and clinical presentations compared to Trichomonas vaginalis.

Correct Answer: C

Rationale: The correct answer is C: Weakly bound to the cell wall. The glycocalyx in bacteria is a protective layer that can be loosely attached to the cell wall or membrane. This loose attachment allows for flexibility and protection against desiccation and immune responses. Choice A is incorrect because the glycocalyx is not strongly bound to the cell wall, as it needs to be able to be shed easily for bacteria to escape host immune responses. Choice B is incorrect because the glycocalyx is not directly involved in bacterial movement, but rather serves as a protective barrier. Choice D is incorrect as the glycocalyx does play a role in bacterial physiology.

Correct Answer: D

Rationale: The correct answer is D: Erysipeloid. Erysipeloid is a bacterial infection caused by Erysipelothrix rhusiopathiae commonly found in animals like cattle. The patient's occupation as a cattle-ranch worker puts them at risk for this infection. Symptoms such as high body temperature, severe headache, carbuncle on the forearm with edema, and regional lymphadenitis are typical of erysipeloid. Anthrax (A) is more associated with skin lesions and severe systemic symptoms. Carcinoma of skin (B) presents differently with slow-growing skin lesions. Erysipelas (C) is a different bacterial infection characterized by red, swollen patches on the skin.

Correct Answer: A

Rationale: The correct answer is A: Bacterial ribosomes synthesize proteins. Ribosomes are cellular organelles responsible for protein synthesis by translating mRNA into amino acids. They are essential for the production of proteins needed for cell function. Choices B, C, and D are incorrect because ribosomes do not synthesize DNA, degrade toxic substances, or assist in cell division. DNA synthesis is carried out by DNA polymerase, degradation of toxic substances is typically done by enzymes, and cell division is primarily regulated by the cell cycle machinery.

Correct Answer: D

Rationale: The correct answer is D: HIV. HIV is transmitted through direct contact with certain body fluids such as blood, semen, vaginal fluids, and breast milk. This direct contact route of transmission makes it different from the other choices. Salmonellosis is typically transmitted through contaminated food or water (not direct contact). Tularemia is usually transmitted through insect bites or contact with infected animals. Rubella is primarily transmitted through respiratory droplets. Therefore, HIV is the only option with a contact route of transmission.

Correct Answer: A

Rationale: The correct answer is A: Bacteriological. This method involves isolating and culturing the causative bacteria from the wound material to determine the species. This allows for further testing to confirm gaseous gangrene and identify the specific pathogen. Choice B: Allergic is incorrect as it pertains to immune responses, not identifying bacteria. Choice C: Bacterioscopic is incorrect as it refers to microscopic examination of bacteria, not species identification. Choice D: Serological is incorrect as it involves testing for antibodies in the blood, not identifying the causative agent directly.

Correct Answer: B

Rationale: The correct answer is B: Sporadic disease. When an infection occurs in several persons without any epidemiological link, it is considered sporadic. This term is used to describe isolated cases that do not form a specific pattern or cluster. It indicates random occurrences and lack of connection between the affected individuals. A: Epidemic refers to a sudden increase in the number of cases of a disease within a specific population or region, usually linked by a common source or exposure. C: Endemic signifies the constant presence of a disease within a specific population or region, with cases occurring at a relatively stable rate. D: Pandemic indicates a global outbreak of a disease affecting a large number of people across multiple countries or continents.

Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum. This bacterium is responsible for causing botulism due to its production of botulinum toxin, which is one of the most potent neurotoxins known. Clostridium botulinum thrives in anaerobic conditions like improperly canned foods. Staphylococcus aureus (B), Bacillus anthracis (C), and Pseudomonas aeruginosa (D) do not produce the botulinum toxin and are not associated with botulism. Staphylococcus aureus is known for causing food poisoning, Bacillus anthracis for anthrax, and Pseudomonas aeruginosa for various infections, but not botulism.