Before a surgery the patient was prescribed a synthetic antiprotozoal drug for prevention of wound infection. The prescribed drug is highly effective against Helicobacter pylori. Name this drug:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Metronidazole is a synthetic antiprotozoal drug commonly used for wound infection prevention. 2. It is highly effective against Helicobacter pylori, a bacterium that causes stomach ulcers. 3. Metronidazole works by disrupting DNA structure in bacteria, leading to their death. 4. Chingamin (Chloroquine) is an antimalarial drug, not effective against Helicobacter pylori. 5. Doxycycline hydrochloride is an antibiotic used for bacterial infections, not specifically for H. pylori. 6. Aciclovir is an antiviral drug used for herpes infections, not effective against H. pylori. Summary: Metronidazole is the correct answer as it is specifically effective against H. pylori and commonly used for wound infection prevention. Other choices are incorrect as they target different types of infections.

Correct Answer: C

Rationale: The correct answer is C: ensure survival under harsh conditions. Bacterial endospores are dormant, resistant structures that form under adverse conditions to protect the bacterial DNA and allow the bacterium to survive extreme environments. This function is crucial for the bacterium's long-term survival. Choice A is incorrect as endospores do not directly produce exotoxins. Choice B is incorrect as endospores do not store nutrients but rather protect the bacterium's genetic material. Choice D is incorrect as endospores do not enhance motility but rather enable survival during unfavorable conditions.

Correct Answer: A

Rationale: The correct answer is A: Clostridium botulinum. This bacterium is responsible for causing botulism due to its production of botulinum toxin, which is one of the most potent neurotoxins known. Clostridium botulinum thrives in anaerobic conditions like improperly canned foods. Staphylococcus aureus (B), Bacillus anthracis (C), and Pseudomonas aeruginosa (D) do not produce the botulinum toxin and are not associated with botulism. Staphylococcus aureus is known for causing food poisoning, Bacillus anthracis for anthrax, and Pseudomonas aeruginosa for various infections, but not botulism.

Correct Answer: C

Rationale: The correct answer is C because both Mycobacterium bovis and Mycobacterium tuberculosis are bacteria that can cause tuberculosis in humans. Mycobacterium bovis primarily infects animals but can be transmitted to humans, while Mycobacterium tuberculosis is the main causative agent of tuberculosis in humans. Therefore, both choices A and B are correct. Choice D is incorrect because we know that Mycobacterium bovis and Mycobacterium tuberculosis are causative agents of tuberculosis in humans.

Correct Answer: B

Rationale: The correct answer is B: Malaria. Fever developing 2 weeks post-blood transfusion is characteristic of malaria due to the incubation period of the parasite. Trypanosomiasis presents earlier, amebiasis usually causes GI symptoms, and toxoplasmosis typically manifests with flu-like symptoms. Malaria is the most likely cause based on the timing and clinical presentation.

Correct Answer: A

Rationale: The correct answer is A: Oxacillin. In AST for Gram-positive bacteria, the antibiotic panel typically includes oxacillin to determine if the bacterium is susceptible or resistant to beta-lactam antibiotics. Oxacillin is commonly used to test for methicillin resistance in Staphylococcus aureus. Tetracycline (B), Tobramycin (C), and Amikacin (D) are not typically included in the Gram-positive antibiotic panel. Tetracycline is more commonly used for Gram-negative bacteria, while Tobramycin and Amikacin are aminoglycosides usually tested in Gram-negative bacterial infections. Therefore, they are not appropriate choices for the Gram-positive antibiotic panel.

Correct Answer: D

Rationale: The correct answer is D because the flu vaccine mainly stimulates systemic immunity, not local immunity. Systemic immunity refers to the immune response throughout the body, while local immunity is specific to a certain area. Choice A is incorrect because the flu vaccine is indeed recommended. Choice B is incorrect as the flu vaccine can be a subunit vaccine, containing only specific antigens. Choice C is incorrect as the flu vaccine is typically administered parenterally, meaning through injection, nasal spray, or oral routes.

Correct Answer: A

Rationale: The correct answer is A: Clostridium perfringens. Clostridium perfringens is a Gram-positive, spore-forming bacterium that is anaerobic and produces gas. It is commonly associated with wound infections and gas gangrene. Clostridium tetani causes tetanus, not wound infections. Clostridium botulinum causes botulism, not typically associated with wound infections. Bacillus anthracis causes anthrax, which does not typically produce gas in wound infections.

Correct Answer: B

Rationale: The correct answer is B because humoral immunity involves the formation of specific antibodies by B cells. B cells differentiate into plasma cells that produce antibodies to target specific antigens. T cells are involved in cell-mediated immunity, not humoral immunity. Choice A is incorrect because T cells do not produce antibodies. Choice C is incorrect as only B cells are responsible for antibody production in humoral immunity. Choice D is incorrect as B cells play a crucial role in the humoral immune response.